Sleep is essential for human well-being, yet the quality and quantity of sleep reduce as age advances. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
30,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Sleep is essential for human well-being, yet the quality and quantity of sleep reduce as age advances. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sleep apnea is regarded as an important risk factor in the pathogenesis of Alzheimer disease (AD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Studies suggest that individuals who experience memory loss may encounter sleep disturbances before noticing other symptoms. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Insomnia has now become a major health problem of global concern, with about 1/3 of the population suffering from sleep problems, a proportion that is still rising year by year. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Obstructive sleep apnea is one of the most common sleep disorders. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease (AD) and age-related macular degeneration (AMD) represent the leading causes of dementia and vision impairment in the elderly, respectively. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Sensory loss in olfaction, vision, and hearing is a risk factor for dementia, but the reasons for this are unclear. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Several studies have been done to investigate the role of hearing loss (HL) in cognitive decline. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Two-hundred and seventy-three subjects were included, 189 normal hearing and 84 subjective hearing loss subjects. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In the course of several neurodegenerative conditions, the presence of a sensory alteration, even before the appearance of cognitive disorders or complaints concerning autonomy, can potentially lead to earlier diagnosis and more efficient management of these complex patients. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In this perspective article, the author explores the connections between hearing loss, central auditory processing, and cognitive decline, offering insights into the complex dynamics at play. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Atrial fibrillation (AF) is the most common cardiac arrhythmia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease (AD) prevalence has increased in the last century which can be attributed to increased lifespan, but environment is also important. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Over 35% of the adult US population is obese. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Due to increasing lifespan and aging populations globally there has been a steep rise in late-life dementia, which is now the second most common cause of death in high-income countries. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Diabetes mellitus (DM) and Alzheimer's disease (AD) are two major health concerns that have seen a rising prevalence worldwide. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Cognition is a mental process that provides the ability to think, know, and learn. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
ObjectiveOlder individuals face a higher likelihood of developing dementia. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Some of these were the same already detected in a population without intellectual disabilities (education, occupation, physical activity, leisure, community and social activities); others were found to be specifically relevant for this population: type of schooling, parental educational level, environmental stimulation and living place. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In a world with an ageing population, dementia has become an urgent threat to global health and wellbeing. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Social connectedness is important for maintaining cognitive function and cognitive health in older age. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
There were nine inclusion/exclusion criteria that were used in more than half of the late life depression AETs: minimum severity on a symptom severity scale (100.0%), significant suicidal ideation (77.8%), psychotic features during the current episode of depression or history of a psychotic disorder (94.4%), history of bipolar disorder (77.8%), diagnosis of alcohol or drug abuse or dependence (83.3%), presence of a comorbid nondepressive, nonsubstance use Axis I disorder (55.6%), episode duration too short (66.7%), and an insufficient score on a cognitive screen (88.3%) or the presence of a cognitive disorder (55.6%). 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We respond to the commentary by Ballenger et al. While appreciating "our provocative article", they called for "a more rigorous historical approach…". 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Ambient fine particulate matter (PM2.5) is a key environmental risk factor closely associated with Alzheimer's disease (AD), although its specific molecular mechanisms remain incompletely elucidated. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The aggregation and prion-like propagation of tau are the hallmarks of Alzheimer's disease (AD) and other tauopathies. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 30,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,180 records, built mostly from automated pulls of Europe PMC (64.2% of the library) and OpenAlex (16.9%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,037 records (3.4% of the library) are not peer-reviewed — 964 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →