27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Participants in the most disadvantaged neighborhoods (n = 156) were younger, more often female, and less often college-educated or white than those in less disadvantaged neighborhoods (n = 1963). 3 key findings →
Participants: 156 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The mean (SD) age of the 4,631 participants was 67.6 (4.89) years, and 2579 (55.7%) were women. 5 key findings →
Design: cross-sectional Participants: 4,943 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Exposure to high neighborhood‐level socioeconomic disadvantage is associated with negative health outcomes. 5 key findings →
Design: longitudinal study Participants: 645 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Multiple sclerosis is a chronic, demyelinating disease of the CNS. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
EGb 761 ® is currently recommended in multiple guidelines for the symptomatic treatment of MCI. 2 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
This untargeted metabolomics study identified potential biomarkers for cognitive function in a cohort of Puerto Rican older adults. 2 key findings →
Participants: 736 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Broad clinical syndromes associated with COVID-19 were classified as a cerebrovascular event (defined as an acute ischaemic, haemorrhagic, or thrombotic vascular event involving the brain parenchyma or subarachnoid space), altered mental status (defined as an acute alteration in personality, behaviour, cognition, or consciousness), peripheral neurology (defined as involving nerve roots, peripheral nerves, neuromuscular junction, or muscle), or other (with free text boxes for those not meeting these syndromic presentations). 4 key findings →
Design: case report Participants: 153 Evidence: low
Full summary, score breakdown and related studies → Original source
Abeta (1-42/1-40) and GFAP independently associated with amyloid PET status (p = 0.009 and p < 0.001 respectively), and GFAP and NfL independently associated with syndrome diagnosis (p = 0.001 and p = 0.048 respectively). 2 key findings →
Participants: 176 Evidence: low
Full summary, score breakdown and related studies → Original source
Web-based cognitive tests have potential for standardized screening in neurodegenerative disorders. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
First, in the normative sample, the total score on the Inbrain CST was significantly affected by age, years of education, and gender. 4 key findings →
Participants: 480 Evidence: low
Full summary, score breakdown and related studies → Original source
Neurodegenerative diseases are a growing burden, and there is an urgent need for better biomarkers for diagnosis, prognosis, and treatment efficacy. 5 key findings →
Participants: 197 Evidence: low
Full summary, score breakdown and related studies → Original source
Increasing evidence suggests Alzheimer's disease (AD) pathophysiology is influenced by primary and secondary bile acids, the end product of cholesterol metabolism. 4 key findings →
Participants: 111 Evidence: low
Full summary, score breakdown and related studies → Original source
Microbial agents including periodontal pathogens have recently appeared as important actors in Alzheimer's disease (AD) pathology. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source
Despite the demonstrated benefits of computerized cognitive training for older adults, little is known about the determinants of training behavior. 3 key findings →
Participants: 219 Evidence: low
Full summary, score breakdown and related studies → Original source
Genome wide association studies (GWAS) of human diseases have generally identified many loci associated with risk with relatively small effect sizes. 2 key findings →
Participants: 1,865 Evidence: low
Full summary, score breakdown and related studies → Original source
We compared regional retention of 18F-flortaucipir between 20 patients with Lewy body disorders (LBD), 12 Alzheimer's disease patients with positive amyloid positron emission tomography (PET) scans (AD+Aβ) and 15 healthy controls with negative amyloid PET scans (HC-Aβ). 1 key finding →
Participants: 20 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The neuropathology of Parkinson's disease dementia (PDD) is heterogenous, and the impacts of each pathophysiology and their synergistic effects are not fully understood. 2 key findings →
Participants: 23 Evidence: low
Full summary, score breakdown and related studies → Original source
The dominant theory of Alzheimer disease (AD) has been that amyloid-β (Aβ) accumulation in the brain is the initial cause of the degeneration leading to cognitive and functional deficits. 3 key findings →
Participants: 144 Evidence: low
Full summary, score breakdown and related studies → Original source
Behavioural variant frontotemporal dementia (bvFTD) is a neurodegenerative disorder often neuropathologically associated with the accumulation of abnormally hyperphosphorylated tau, for which there is currently no disease-modifying treatment. 2 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
The revised UCLA loneliness scale score was not significantly associated with age, years of education, mini-mental state examination (MMSE) score, gender, living status, visual impairment, hearing impairment, and marital status. 5 key findings →
Participants: 152 Evidence: low
Full summary, score breakdown and related studies → Original source
Individual's loneliness was stable when their spouse's cognition remained normal, but increased with the spouse's TCIND. 4 key findings →
Participants: 2,206 Evidence: low
Full summary, score breakdown and related studies → Original source
Among the compounds detected in greater abundance in the CSF of patients with DLB compared with patients with AD, only one had a xenobiotic profile potentially related to the pathophysiology of DLB. 5 key findings →
Participants: 45 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Black older adults are less likely to move to assisted living and are more likely to move to a nursing home compared to white older adults. 3 key findings →
Participants: 5,212 Evidence: low
Full summary, score breakdown and related studies → Original source
The most observed resident affect type was neutral (53.1% of all minutes observed), followed by positive affect (44.5%). 5 key findings →
Participants: 22 Evidence: low
Full summary, score breakdown and related studies → Original source
Presentation age was similar between groups (median 74-75 years). 5 key findings →
Participants: 1,782 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →