Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The American Heart Association's LS7 score identified individuals who were vulnerable to multiple chronic nonvascular conditions. 4 key findings →
Participants: 6,506 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Public health guidelines recommend exercise as a key lifestyle intervention for promoting and maintaining healthy sleep function and reducing disease risk. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Due to the continuous aging of the population and consequent increase in dementia, focus on its prevention is of growing importance for public health. 4 key findings →
Participants: 73 Evidence: low
Full summary, score breakdown and related studies → Original source
The main form of vitamin D in all brain regions measured was 25(OH)D3 . 5 key findings →
Participants: 290 Evidence: low
Full summary, score breakdown and related studies → Original source
Increased UPF consumption is associated with higher risks of dementia, CIND, and CIND or dementia among US older adults. 4 key findings →
Design: cohort Participants: 5,370 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
This study investigated the benefits of resistance training on cognition in patients with mild cognitive impairment. 2 key findings →
Design: meta-analysis Evidence: early
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The prevalence of obesity has increased worldwide in the past ~50 years, reaching pandemic levels. 1 key finding →
Evidence: low
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An estimated 47 million people worldwide are living with dementia in 2015, and this number is projected to triple by 2050. 3 key findings →
Evidence: low
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For hypertension, CHD, and stroke, there is convincing evidence that increasing the consumption of vegetables and fruit reduces the risk of disease. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The past 3 decades have been characterized by an exponential growth in knowledge and advances in the clinical treatment of atrial fibrillation (AF). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
More than 25 million people in the world today are affected by dementia, most suffering from Alzheimer's disease. 5 key findings →
Evidence: low
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Mild Alzheimer's disease is the leading cause of dementia, accounting for 50-70% of cases. 5 key findings →
Evidence: low
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Suffering related to dementia is multifaceted because cognitive and physical functioning slowly deteriorates. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a healthcare burden of epidemic proportions for which there is currently no cure. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dementia is one of the greatest global challenges for health and social care in the 21st century. 1 key finding →
Evidence: low
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Depression predisposes to medical illnesses and advances biological aging indicated by shorter telomere length, accelerated brain aging and advanced epigenetic aging. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
There is a strong association between late-life depression, cognitive impairment, cerebrovascular disease, and poor cognitive outcomes, including progressive dementia, especially Alzheimer's disease. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Higher intake of calories and fats may be associated with higher risk of AD in individuals carrying the apolipoprotein E epsilon4 allele. 5 key findings →
Participants: 980 Evidence: low
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The notion of what qualifies as vascular dementia has varied greatly since the first mention of dementia after apoplexy in ancient literature. 5 key findings →
Evidence: low
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A diet rich in salt is linked to an increased risk of cerebrovascular diseases and dementia, but it remains unclear how dietary salt harms the brain. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
From an ethical perspective, important benefits of embodied AI applications in mental health include new modes of treatment, opportunities to engage hard-to-reach populations, better patient response, and freeing up time for physicians. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer's disease (AD), the leading cause of dementia, is characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alcoholism is a possible cause of dementia, mainly through associated nutritional deficiencies and, rarely, through acute direct toxicity. 1 key finding →
Participants: 3,777 Evidence: low
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Vascular contributions to cognitive impairment and dementia (VCID) are characterized by the aging neurovascular unit being confronted with and failing to cope with biological insults due to systemic and cerebral vascular disease, proteinopathy including Alzheimer's biology, metabolic disease, or immune response, resulting in cognitive decline. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →