31,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
In our large population-based sample, frailty syndrome was a short-term predictor of overall dementia and VaD. 5 key findings →
Design: longitudinal study Participants: 2,581 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The prevalence of older patients with dementia and oropharyngeal dysphagia (OD) is rising and management is poor. 1 key finding →
Design: longitudinal study Participants: 255 Evidence: moderate
Full summary, score breakdown and related studies → Original source
ChEIs may increase the risk of syncope, with no effects on falls, fracture, or accidental injury in cognitively impaired older adults. 2 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source
DSD is a strong predictor of functional dependence, institutionalization, and mortality in older patients admitted to a rehabilitation setting, suggesting that strategies to detect DSD routinely in practice should be developed and DSD should be included in prognostic models of health care. 4 key findings →
Design: cohort study Participants: 2,642 Evidence: moderate
Full summary, score breakdown and related studies → Original source
There is lack of sound studies examining fall risk factors in cognitively impaired elders. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Our sample included 11,105 patients (median age 77, 51% female), with 2299 in the hallway group and 8806 in the non-hallway group. 5 key findings →
Design: retrospective cohort Participants: 11,105 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Delirium prolongs hospitalization for persons with dementia. 2 key findings →
Design: cohort study Participants: 139 Evidence: moderate
Full summary, score breakdown and related studies → Original source
A total of 17 studies met the inclusion criteria. 5 key findings →
Design: prospective cohort Participants: 17 Evidence: moderate
Full summary, score breakdown and related studies → Original source
In a longitudinal study of senile dementia and healthy aging, the occurrence of serious falls was examined in participants with senile dementia of the Alzheimer's type (SDAT) (n = 44) and in cognitively healthy elderly control participants (n = 56) over a 4-year period. 4 key findings →
Design: longitudinal study Participants: 44 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Anemia among older adults aged ≥ 60 years is a well-described risk factor that increases the risk of falls, cardiovascular diseases, and mortality. 4 key findings →
Design: longitudinal study Participants: 3,252 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Ultimately, 10,373 participants were included in the analysis. 5 key findings →
Design: longitudinal study Participants: 10,373 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Compared with non-dementia patients, hospitalised dementia patients have higher rates of potentially preventable complications that might be responsive to nursing interventions. 4 key findings →
Design: retrospective cohort Evidence: moderate
Full summary, score breakdown and related studies → Original source
After adjusting for potentially confounding variables such as age, gender, and comorbidities, we found that individuals with mild dementia (HR 1.74 [95% confidence interval (CI) 1.12 to 2.70]; p = 0.01) and moderate to severe dementia (HR 3.05 [95% CI 1.80 to 5.17]; p < 0.001) both demonstrated elevated hazards of death compared with patients without dementia. 5 key findings →
Participants: 156,596 Evidence: moderate
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Of the patients, 82.2% were receiving at least one dizziness-associated medication and 71.2% at least one hypotension-associated medication. 5 key findings →
Design: cohort study Participants: 210 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
This was a retrospective analysis using nationally representative UK general practice population between 1998 and 2018, from electronic health records (Clinical Practice Research Datalink, CPRD, GOLD). 5 key findings →
Participants: 1,219,732 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Circadian rhythms in elderly patients with severe dementia and behavioral disorders such as wandering, agitation and/or delirium were examined. 1 key finding →
Participants: 24 Evidence: low
Full summary, score breakdown and related studies → Original source
Over a median follow-up of 5.9-7.9 years, 3,492 dementia cases were identified. 5 key findings →
Participants: 44,488 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Changes in gait, especially decreased gait velocity, may be a harbinger of cognitive decline in aging. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
In this study, 97 patients with senile dementia of the Alzheimer type (SDAT) in a nursing home were followed over a period of 2 years, and the relationship between falls and gait function was examined. 4 key findings →
Participants: 97 Evidence: low
Full summary, score breakdown and related studies → Original source
The daily rhythm in serum melatonin levels was measured in patients with dementia of the degenerate type (Alzheimer's disease, Pick's disease and senile dementia of the Alzheimer type) by radioimmunoassay. 2 key findings →
Participants: 13 Evidence: low
Full summary, score breakdown and related studies → Original source
Oropharyngeal dysphagia (OD) is a highly prevalent geriatric syndrome that remains underdiagnosed and undertreated, often resulting in severe nutritional and respiratory complications with poor clinical outcomes. 5 key findings →
Design: narrative review Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Study 1 showed that each person's financial strain was associated with their own greater depressive symptoms. 2 key findings →
Participants: 147 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
376 323 elective geriatric THA patient samples from the NIS database were included, with an overall dementia prevalence of 2.05%. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer's disease and related dementias (ADRD) affects millions of patients worldwide and is a leading cause of morbidity in older adults. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Delirium and dementia share similarities in clinical and pathogenic features, leading to the speculation that instead of being distinct clinical entities, the two age-related conditions may be linked by a common pathogenic mechanism. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 31,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 31,380 records, built mostly from automated pulls of Europe PMC (65.6% of the library) and OpenAlex (16.2%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,048 records (3.3% of the library) are not peer-reviewed — 973 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →
Newest studies, as a dated timeline → Atom feed Where this research is being discussed: events