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Research

31,380 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 1–25 of 86 studies in Risk factors published 2024 · free to read (page 1 of 4) · 31,380 in the whole library · How the 0–100 score works

Download bibliography of these 86 studies, in this order: BibTeX (.bib) · RIS (.ris)

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Other subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 16,851 studies have no institution on record and are not counted here.

What “Risk factors” covers

Risk factors — Conditions, exposures and habits linked to a higher or lower chance of dementia, and how strong each link is.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Traumatic Brain Injury and Risk of Incident Comorbidities

✓ Peer-reviewed alzhub usefulness score 67 out of 100. JAMA Network Open 2024-12-12

The study consisted of 20 400 patients (9264 female [45.4%]; 1576 Black [7.7%], 3944 Latinx [19.3%], and 10 480 White [51.4%]), including 5100 patients with mTBI (median [IQR] age, 36.0 [25.0-51.0] years), 5100 patients with msTBI (median [IQR age, 35.0 [25.0-52.0] years), and 10 200 matched patients in the control group (median [IQR] age, 36.0 [25.0-51.0] years). 5 key findings →

Design: cohort study Participants: 400 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Geographical variation in dementia prevalence across China: a geospatial analysis

✓ Peer-reviewed alzhub usefulness score 60 out of 100. The Lancet Regional Health - Western Pacific 2024-06-01

The weighted prevalence of dementia at provincial level in China in 2018 ranged from 2.62% (95%BCI: 1.70%, 3.91%) to 13.53% (95%BCI: 8.82%, 20.93%). 5 key findings →

Design: longitudinal study Participants: 17,176 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Prevalence of Unrecognized Cognitive Impairment in Federally Qualified Health Centers

✓ Peer-reviewed alzhub usefulness score 60 out of 100. JAMA Network Open 2024-10-22

A total of 844 eligible individuals were consecutively approached, 294 consented to participate, and 204 completed the study (mean [SD] age, 70.0 [5.1] years; 127 women [62.3%]). 5 key findings →

Design: cross-sectional Participants: 127 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Potential Effects of Long-Term Exposure to Air Pollution on Dementia: A Longitudinal Analysis in American Indians Aged 55 Years and Older

✓ Peer-reviewed alzhub usefulness score 54 out of 100. International Journal of Environmental Research and Public Health 2024-01-24

The average PM2.5 levels in the IHS counties were lower than those in all US counties, while the mean O3 levels in the IHS counties were higher than the US counties. 4 key findings →

Design: cohort study Participants: 26,871 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Factors associated with incentive redemption among participants in a multicenter prospective syncope clinical study

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Academic Emergency Medicine 2024-06-28

Incentives are a cornerstone of attracting and retaining participants in clinical research studies.1 They serve as compensation for the time and effort individuals dedicate to the research process.1 However, previous randomized clinical trials found incentivizing was not associated with increased rates of clinical trial recruitment.2, 3 Furthermore, the rate participants redeem these incentives can vary considerably.1, 4 Although numerous methods have been used to increase trial recruitment, no studies have been conducted to explore factors associated with incentive redemption, regardless of clinical area. 5 key findings →

Design: cohort study Participants: 586 Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

Social Determinants of Health, Risk and Resilience against Alzheimer’s Disease and Related Dementias: The Healthy Brain Initiative

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of Alzheimer s Disease Reports 2024-01-09

Perceived greater access to greenspaces (estimate = 2.83, 95% CI = 1.40–4.26) and greater time in neighborhood greenspaces were associated with greater RI scores (estimate = 2.30, 95% CI = 1.24–3.35). 5 key findings →

Design: cross-sectional Participants: 162 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Can integration of Alzheimer’s plasma biomarkers with MRI, cardiovascular, genetics, and lifestyle measures improve cognition prediction?

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Brain Communications 2024-01-01

For amyloid positive individuals Aβ42/Aβ40, glial fibrillary acidic protein and p-tau181 were the top predictors of cognitive decline while Aβ42/Aβ40 was prominent for amyloid negative participants across all age groups. 5 key findings →

Design: cross-sectional Participants: 1,185 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Home Health Quality among Hospitalized Older Adults with Alzheimer's Disease and Related Dementia: Association with Race/Ethnicity and Dual Eligibility before and during the COVID Pandemic

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of the American Medical Directors Association 2024-06-07

During the COVID-19 pandemic, home health agencies (HHAs) discharges following acute hospitalizations increased. 1 key finding →

Design: cohort study Participants: 426,766 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Post‐acute care transitions during COVID ‐19: Racial, ethnic, and socioeconomic differences in older adults with Alzheimer's disease and related dementia

✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of the American Geriatrics Society 2024-03-27

SNF discharges decreased while home and HHA discharges increased during the pandemic. 5 key findings →

Participants: 830,656 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Geographic disparities in Alzheimer's disease and related dementia mortality in the US: Comparing impacts of place of birth and place of residence

✓ Peer-reviewed alzhub usefulness score 50 out of 100. SSM - Population Health 2024-08-23

We found that both state of birth and state of residence account for a modest portion of ADRD mortality variation. 5 key findings →

Design: longitudinal study Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Geographic Variation of Antidementia and Antipsychotic Medication Use Among US Nursing Home Residents With Dementia

✓ Peer-reviewed alzhub usefulness score 49 out of 100. Medical Care 2024-05-29

memantine, cholinesterase inhibitor (ChEI), antipsychotic use] estimated adjusted odds ratios (aOR) and 95% CIs for resident, facility, and HRR characteristics. 5 key findings →

Participants: 9,735 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

The relationship between neighborhood disadvantage and the brain age gap

✓ Peer-reviewed alzhub usefulness score 49 out of 100. Alzheimer s & Dementia 2024-12-01

This analysis found that the mean brain age gap does not significantly differ between Quintile 5 and Quintiles 1‐4 (p≤0.45), however statistical power was low given very broad confidence intervals. 3 key findings →

Design: longitudinal study Participants: 1,052 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

On the Opportunities and Challenges of Foundation Models for GeoAI (Vision Paper)

✓ Peer-reviewed alzhub usefulness score 48 out of 100. ACM Transactions on Spatial Algorithms and Systems 2024-03-20

Large pre-trained models, also known as foundation models (FMs), are trained in a task-agnostic manner on large-scale data and can be adapted to a wide range of downstream tasks by fine-tuning, few-shot, or even zero-shot learning. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Ready for Discharge, but Are They Ready to Go Home? Examining Neighborhood-Level Disadvantage as a Marker of the Social Exposome and the Swallowing Care Process in a Retrospective Cohort of Inpatients With Dementia

✓ Peer-reviewed alzhub usefulness score 47 out of 100. American Journal of Speech-Language Pathology 2024-03-19

ADI was significantly higher in this cohort ( M = 3.84, SD = 2.58) than in the surrounding county ( M = 2.79, SD = 1.88, p = .000). 5 key findings →

Participants: 204 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

The Association of Neighborhood Socioeconomic Status with Executive Function and Processing Speed in Cognitively Normal Mexican American Elders from the Health and Aging Brains Study: Health Disparities Cohort

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Dementia and Geriatric Cognitive Disorders 2024-01-01

MAs were younger, more likely to be female, less educated, had higher ADI scores, performed worse on trails B (all p < 0.05), and had lower prevalence of APOE4 + when compared to NHWs (p < 0.0001). 5 key findings →

Design: longitudinal study Participants: 1,312 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Neighborhood Racial and Ethnic Segregation and the Risk of Dementia in Older Adults Living with Kidney Failure

✓ Peer-reviewed alzhub usefulness score 46 out of 100. Journal of the American Society of Nephrology 2024-04-26

Key Points Regardless of race and ethnicity, older adults with kidney failure residing in or receiving care at dialysis facilities located in high-segregation neighborhoods were at a 1.63-fold and 1.53-fold higher risk of dementia diagnosis, respectively. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Prevalence of dementia diagnosis in Sweden by geographical region and sociodemographic subgroups: a nationwide observational study

✓ Peer-reviewed alzhub usefulness score 45 out of 100. The Lancet Regional Health - Europe 2024-08-16

At the end of 2022, 3.7% (92,293/2,483,798) of people aged ≥62 years in Sweden had a dementia diagnosis from specialist care or drug prescriptions and varied from 0.6% in ages 62-69 to 14.8% in ages ≥90. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Geospatial Analysis of the Association Between Medicaid Expansion, Minimum Wage Policies, and Alzheimer’s Disease Dementia Prevalence in the United States

✓ Peer-reviewed alzhub usefulness score 45 out of 100. Information 2024-11-01

Previous studies indicate that increased healthcare access through Medicaid expansion and alleviation of socioeconomic stressors via higher minimum wages improved health outcomes. 5 key findings →

Participants: 311 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomized / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multicenter collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 31,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 31,380 records, built mostly from automated pulls of Europe PMC (65.6% of the library) and OpenAlex (16.2%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,048 records (3.3% of the library) are not peer-reviewed — 973 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed    Where this research is being discussed: events