31,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Examining the risk of clinically diagnosed dementia in older adults, our study found a 65% increased risk of Alzheimer's disease (AD) dementia in individuals with diabetes compared with those without. 5 key findings →
Design: cohort study Evidence: moderate
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Higher ARTS score was associated (all ps < 0.01) with incident MCI (hazard ratio [HR] = 1.29), dementia (HR = 1.33), and stroke (HR = 1.52) and with diastolic/systolic blood pressure, self-reported hypertension, claudication, congestive heart failure, smoking, and glomerular filtration rate in the combined sample. 5 key findings →
Participants: 707 Evidence: low
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Dementia prevalence exceeds 40% for individuals in advanced old age, but that figure is not informative about the lifetime risk of ever having dementia or the risk of having dementia for different durations. 3 key findings →
Design: longitudinal study Evidence: moderate
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The results suggest that education is robustly associated with level of cognitive function but not with rate of cognitive decline and that the former association primarily accounts for education's correlation with risk of dementia in old age. 2 key findings →
Evidence: low
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We determined the relationship between apolipoprotein (Apo)E, MRI, and low cognitive scores. 1 key finding →
Evidence: low
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Prevalence, 3-year incidence, and types of dementia are comparable in Black and White elderly in the Piedmont area of North Carolina. 3 key findings →
Participants: 4,136 Evidence: low
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While educational disparities in dementia incidence are well-known, whether and to what extent they persist beyond dementia onset is less explored. 4 key findings →
Design: longitudinal study Evidence: moderate
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Older adults in rural India experience higher social isolation due to limited social and healthcare resources. 1 key finding →
Design: longitudinal study Participants: 71,513 Evidence: moderate
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IL-6 levels were negatively associated with performance on the MMSE in this multiethnic cohort. 5 key findings →
Design: cross-sectional Evidence: moderate
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Ninety-seven men (incidence rate: 14.4/1,000) and 183 women (Incidence rate: 19.0/1,000) developed dementia during 8 years of follow-up. 3 key findings →
Evidence: moderate
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These data suggest that older adults in rural communities may be underdiagnosed with ADRD, and/or diagnosed at later stages of dementia. 3 key findings →
Evidence: low
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A substantial minority of patients with dementia exhibit physically aggressive behavior, and this aggression is strongly linked with the presence of depressive symptoms. 2 key findings →
Participants: 541 Evidence: low
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Parental death during childhood is associated with higher prevalence of AD, with different critical periods for father's versus mother's death, with strength of these associations attenuated by remarriage of the widowed parent. 5 key findings →
Participants: 4,108 Evidence: low
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Risk of dementia by age 80 was more pronounced for Hispanic and black men compared with white men. 2 key findings →
Evidence: low
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Dementia is an important cause of morbidity in the geriatric population in this community, where families take responsibility for the care of relatives with dementia. 3 key findings →
Participants: 2,067 Evidence: low
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These results suggest that mechanisms leading to atherosclerosis might also lead to an increased number of perivascular spaces. 5 key findings →
Participants: 706 Evidence: low
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NLR may be useful to identify and stratify patients who could benefit from adjunctive anti-inflammatory treatment. 1 key finding →
Design: cross-sectional Evidence: low
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Half of the participants were over 70, with no formal education. 5 key findings →
Participants: 567 Evidence: moderate
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Obesity is a significant health crisis affecting more than 123 million adults and children/adolescents in the US. 5 key findings →
Design: narrative review Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia research lacks appropriate representation of diverse groups who often face substantial adversity and greater risk of dementia. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
There is little direct evidence that underground railway particulate matter exposure is more harmful than ambient particulate matter exposure. 5 key findings →
Evidence: low
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High Resolution Image Download MS PowerPoint Slide Fine particulate matter (PM 2.5 ) is linked to dementia risk, but ultrafine particles (UFPs, <100 nm) may be even more toxic due to their distinct physicochemical properties. 2 key findings →
Evidence: low
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Disparities in incidence of NDD between Black and White beneficiaries narrowed by 0.37 per 100 person-years from 2014 to 2017. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Asia is the most populous region in the world and its rapidly growing societies are the sources of global development. 2 key findings →
Evidence: low
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With increased numbers of older people a higher burden of neurological disorders worldwide is predicted. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 31,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 31,380 records, built mostly from automated pulls of Europe PMC (65.6% of the library) and OpenAlex (16.2%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,048 records (3.3% of the library) are not peer-reviewed — 973 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →
Newest studies, as a dated timeline → Atom feed Where this research is being discussed: events