27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
The percentage of new enrollees with an ADRD code dropped significantly during the months of IMPACT passage (-1.42 percentage points; 95% CI, -2.13 to -0.71) and implementation (-1.98 percentage points; 95% CI, -2.70 to -1.26) but rose again during the following months. 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
The sense of food insecurity in a group of elderly people may be determined by the perception of distance to food outlets. 1 key finding →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Case conferencing provides opportunities to improve care palliative care outcomes for older people with dementia by engaging family and all relevant internal and external health providers in prospective care planning. 4 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Atrial fibrillation already accounts for a significant amount of National Health Service (NHS) funding, and over the coming years is highly likely to impose a growing cost on NHS budgets and the wider UK healthcare system. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Microglia are the resident macrophages of the central nervous system. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Emerging evidence indicates that gut microbiota is important in the regulation of brain activity and cognitive functions. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The worldwide cost of dementia has increased by 34% (18% in fixed prices) between 2005 and 2009. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
In 2019, the global VSL-based economic burden of ADRDs was an estimated $2.8 trillion. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
China's population has rapidly aged over the recent decades of social and economic development as neurodegenerative disorders have proliferated, especially Alzheimer's disease (AD) and related dementias (ADRD). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Earlier treatment leads to a small delay in institutionalization among AD patients, resulting in significant costs savings to Medicaid. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The strongest genetic risk factor for late-onset Alzheimer's disease (AD) is allelic variation of the APOE gene, with the following risk structure: ε4 > ε3 > ε2. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Older adults classified with dementia were more likely to drop out of the labor force and become poor than similar older adults without dementia. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Participants indicated skepticism regarding the use of precision medicine in their communities. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We found that four items-a Medicare claim recording ADRD 1 year ago, 2 years ago, 3 years ago, and a total stay of 6 months in a nursing home-exhibit a pattern of association consistent with a single underlying ADRD construct, and presence of any two of these four items predict a direct measure of cognitive function and also future claims for ADRD. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The results of the simulations show that by prolonging the length of a person's 'stay' in the Mild, Moderate, or Severe stage, the total cost of care for all persons with AD will increase by 2080. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Out-of-pocket costs of dementia care were collected via a web-based weekly survey for up to 18 months. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
We examined how methods used for identifying dementia in administrative claims affected dementia incidence across racial/ethnic populations using a 100% sample of Medicare beneficiaries (n = 23,793,452). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
This study aims to analyze the relationship between cognitive function and out-of-pocket cost of the state change of multiple chronic conditions in individuals aged 60 or older. 3 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Early-diagnosed patients (N = 421) have a lower utilization rate of inpatient skilled nursing facility, nursing home and hospitalization than late-diagnosed patients (N = 2817) after being diagnosed with AD. 5 key findings →
Design: case-control study Participants: 421 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
In January 2020, the Centers for Medicare & Medicaid Services implemented the Patient-Driven Groupings Model (PDGM), the most substantial revision to Medicare's home health (HH) prospective payment system since its introduction in 2000. 1 key finding →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Alzheimer's disease and related diseases (ADRD) is a progressive and inexorable disease. 2 key findings →
Participants: 120 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Many rural American Indian and Alaska Native (AIAN) veterans receive care from the Indian Health Service (IHS). 4 key findings →
Participants: 12,242 Evidence: low
Full summary, score breakdown and related studies → Original source
Differences in system‐level factors such as access to dementia specialists is a contributing factor to differences in diagnosis rates in MA and TM. 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
The proteolytic cleavage of Alzheimer beta-amyloid precursor protein (APP) and signaling receptor Notch is mediated by the PS/gamma-secretase complex, which consists of presenilins, nicastrin, APH-1, and PEN-2. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Beneficiaries with a new diagnosis of Alzheimer disease and related dementias, hypertension, and psychiatric disorders had relatively high rates of switching into MA plans and low rates of switching out of MA plans. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
10 of the 705 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →