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Newest in this topic

  1. A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model 2022-07-08
  2. In vivo imaging of synaptic loss in Alzheimer's disease with [18F]UCB-H positron emission tomography 2019-08-29
  3. Cross-interaction of tau PET tracers with monoamine oxidase B: evidence from in silico modelling and in vivo imaging 2019-03-27

Studies

4 studies carry this tag.

Date range

2012 to 2022

Top journals

  • European journal of nuclear medicine and molecular imaging 3
  • PloS one 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. European journal of nuclear medicine and molecular imaging 2022-07-08 Drug development

    Our imaging platform has enabled the quantification of tau depositions and consequent neuronal loss and is potentially applicable to the evaluation of candidate anti-tau and neuroprotective drugs.

  2. In vivo imaging of synaptic loss in Alzheimer's disease with [18F]UCB-H positron emission tomography

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. European journal of nuclear medicine and molecular imaging 2019-08-29 Brain scans and imaging

    The findings thus highlight predominant synaptic loss in the hippocampus, confirming previous autopsy-based studies and a recent PET study with an 11C-labelled SV2A radiotracer. [18F]UCB-H PET allows to image in vivo synaptic changes in Alzheimer's disease and to relate them to patients' cognitive impairment.

  3. Cross-interaction of tau PET tracers with monoamine oxidase B: evidence from in silico modelling and in vivo imaging

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. European journal of nuclear medicine and molecular imaging 2019-03-27 Brain scans and imaging

    The developed tau tracers show in silico and in vivo evidence of cross-interaction with MAO-B; the MAO-B component of the tracer binding was dependent on the regional concentration of the enzyme.

  4. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. PloS one 2012-12-31 Brain scans and imaging

    Tauopathies are widespread neurodegenerative disorders characterised by the intracellular accumulation of hyperphosphorylated tau.

All topic tags with their study counts