Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. Precision therapeutic strategies for Alzheimer's disease: Amyloid β-targeted foundations and multimodal next-generation approaches 2025-12-30
  2. The multifaceted roles of apolipoprotein E4 in Alzheimer's disease pathology and potential therapeutic strategies 2025-07-08
  3. Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease 2024-01-01

Studies

10 studies carry this tag.

Date range

2002 to 2025

Top journals

  • CNS & neurological disorders drug targets 1
  • Cell death discovery 1
  • Current neuropharmacology 1
  • Journal of Korean medical science 1
  • Molecular and cellular neurosciences 1

10 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Precision therapeutic strategies for Alzheimer's disease: Amyloid β-targeted foundations and multimodal next-generation approaches

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Molecular and cellular neurosciences 2025-12-30 Treatments

    Alzheimer's disease (AD) is the leading cause of dementia and a significant unmet medical challenge, pathologically characterized by amyloid β (Aβ) aggregation, tau hyperphosphorylation, synaptic dysfunction, and chronic neuroinflammation.

  2. The multifaceted roles of apolipoprotein E4 in Alzheimer's disease pathology and potential therapeutic strategies

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Cell death discovery 2025-07-08 Treatments

    Alzheimer's disease (AD), the most common dementia in the elderly, is marked by progressive cognitive decline and neurodegeneration.

  3. Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. The journal of prevention of Alzheimer's disease 2024-01-01 TREM2 and immune genetics

    Alzheimer's disease (AD) is an age-related degenerative disease, which is characteristic by the deposition of senile plaques (SP) outside the cells, the neurofibrillary tangles (NFTs) inside the neurons, and the loss of synapse and neurons.

  4. Underlying Mechanisms of Brain Aging and Neurodegenerative Diseases as Potential Targets for Preventive or Therapeutic Strategies Using Phytochemicals

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Nutrients 2023-08-04 TREM2 and immune genetics

    During aging, several tissues and biological systems undergo a progressive decline in function, leading to age-associated diseases such as neurodegenerative, inflammatory, metabolic, and cardiovascular diseases and cancer.

  5. Current Status of Drug Targets and Emerging Therapeutic Strategies in the Management of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Current neuropharmacology 2020-01-01 Drug development

    Alzheimer's disease (AD) is a chronic neurodegenerative disease affecting the elderly.

  6. Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Progress in neurobiology 2018-12-30 Genetics

    AD is a progressive neurodegenerative disorder and a leading cause of dementia in an aging population worldwide.

  7. Novel Therapeutic Strategies for Dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. CNS & neurological disorders drug targets 2016-01-01 Drug development

    Dementia represents a major problem of health and disability, with a relevant economic impact on our society.

  8. Diverse molecular targets for therapeutic strategies in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Korean medical science 2014-07-11 Drug development

    Alzheimer's disease (AD) is the most common form of dementia caused by neurodegenerative process and is tightly related to amyloid β (Aβ) and neurofibrillary tangles.

  9. Intercellular transfer of tau aggregates and spreading of tau pathology: Implications for therapeutic strategies

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropharmacology 2013-09-17 Drug development

    Filaments made of hyperphosphorylated tau protein are encountered in a group of neurodegenerative disorders termed tauopathies.

  10. Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Trends in pharmacological sciences 2002-07-01 Treatments

    The amyloid and tangle cascade hypothesis is the dominant explanation for the pathogenesis of Alzheimer's disease (AD).

All topic tags with their study counts