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Newest in this topic

  1. TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain 2023-08-18
  2. Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation 2022-07-11
  3. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis 2022-01-05

Studies

7 studies carry this tag.

Date range

2013 to 2023

Top journals

  • Acta neuropathologica 1
  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 1
  • PLoS genetics 1
  • PloS one 1
  • Progress in neurobiology 1

7 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Science advances 2023-08-18 TREM2 and immune genetics

    Immunological control of viral infections in the brain exerts immediate protection and also long-term maintenance of brain integrity.

  2. Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022-07-11 TREM2 and immune genetics

    STZ/I.C.V is an effective way to induce AD mice model, with not only AD-like neuropsychiatric behaviors, but also typic AD-like neuropathological features including neurofibrillary tangles, deposit of β-amyloid (Aβ), neuroinflammation, and imbalanced synaptic plasticity.

  3. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2022-01-05 Biomarkers

    Alzheimer's disease (AD) is a debilitating dementia characterized by progressive memory loss and aggregation of amyloid-β (Aβ) protein into amyloid plaques in patient brains.

  4. Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Progress in neurobiology 2018-12-30 Genetics

    AD is a progressive neurodegenerative disorder and a leading cause of dementia in an aging population worldwide.

  5. Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Acta neuropathologica 2017-01-12 Genetics

    Dysregulated proteostasis is a key feature of a variety of neurodegenerative disorders.

  6. Cerebrospinal fluid (CSF) 42 amino acid species of amyloid beta (Aβ42) and tau levels are strongly correlated with the presence of Alzheimer's disease (AD) neuropathology including amyloid plaques and neurodegeneration and have been successfully used as endophenotypes for genetic studies of AD.

  7. Th17 cell-mediated neuroinflammation is involved in neurodegeneration of aβ1-42-induced Alzheimer's disease model rats

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2013-10-04 Tau biomarkers

    Neuroinflammation, especially innate immunocyte-mediated neuroinflammation, has been reported to participate in pathogenesis of Alzheimer's disease (AD).

All topic tags with their study counts