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Home › Research › Topics › tau-fibrils

tau-fibrils

2 studies tagged tau-fibrils, dated 2020-02-28 to 2021-06-21. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Cryptic Sites in Tau Fibrils Explain the Preferential Binding of the AV-1451 PET Tracer toward Alzheimer's Tauopathy 2021-06-21
  2. Computational Insight into the Binding Profile of the Second-Generation PET Tracer PI2620 with Tau Fibrils 2020-02-28

Studies

2 studies carry this tag.

Date range

2020 to 2021

Top journals

  • ACS chemical neuroscience 2

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Cryptic Sites in Tau Fibrils Explain the Preferential Binding of the AV-1451 PET Tracer toward Alzheimer's Tauopathy

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. ACS chemical neuroscience 2021-06-21 Brain scans and imaging

    In contrast, tau tracer AV-1451 is reported to bind to specific types of tau fibrils (in particular to AD-associated and CTE) with higher binding affinity and only show nonspecific or weaker binding toward tau fibrils dominant with 3R isoforms (associated with PiD).

  2. Computational Insight into the Binding Profile of the Second-Generation PET Tracer PI2620 with Tau Fibrils

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. ACS chemical neuroscience 2020-02-28 Brain scans and imaging

    Abnormal deposition of hyperphosphorylated tau as neurofibrillary tangles (NFTs) is an important pathological hallmark of Alzheimer's disease (AD) and of other neurodegenerative disorders.

All topic tags with their study counts