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Home › Research › Topics › second-generation

second-generation

3 studies tagged second-generation, dated 2016-07-07 to 2021-02-16. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Clinical validity of second-generation tau PET tracers as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework 2021-02-16
  2. Computational Insight into the Binding Profile of the Second-Generation PET Tracer PI2620 with Tau Fibrils 2020-02-28
  3. Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device 2016-07-07

Studies

3 studies carry this tag.

Date range

2016 to 2021

Top journals

  • ACS chemical neuroscience 1
  • Alzheimer's research & therapy 1
  • European journal of nuclear medicine and molecular imaging 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Clinical validity of second-generation tau PET tracers as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. European journal of nuclear medicine and molecular imaging 2021-02-16 Brain scans and imaging

    The current literature provides overall preliminary evidence on the establishment of the second-generation tau PET tracers into the clinical context, thereby successfully addressing some methodological issues from the tau PET tracer of the first generation.

  2. Computational Insight into the Binding Profile of the Second-Generation PET Tracer PI2620 with Tau Fibrils

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. ACS chemical neuroscience 2020-02-28 Brain scans and imaging

    Abnormal deposition of hyperphosphorylated tau as neurofibrillary tangles (NFTs) is an important pathological hallmark of Alzheimer's disease (AD) and of other neurodegenerative disorders.

  3. Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Alzheimer's research & therapy 2016-07-07 Biomarkers

    The data derived from this patient cohort demonstrate the safety and tolerability of sustained NGF release by a second-generation NGF-ECB implant to the basal forebrain, with uneventful surgical implant and removal of NGF-ECB implants in a new dosing cohort of four patients with AD.

All topic tags with their study counts