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rat-cortical
3 studies tagged rat-cortical, dated 1992-07-01 to 2008-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation 2008-11-01
- Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons 2003-05-06
- gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine 1992-07-01
Studies
3 studies carry this tag.
Date range
1992 to 2008
Top journals
- European journal of pharmacology 1
- The European journal of neuroscience 1
- The Journal of pharmacology and experimental therapeutics 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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It has been suggested that accumulation of beta-amyloid (Abeta) peptide triggers neurodegeneration, at least in part, via glutamate-mediated excitotoxicity in Alzheimer's disease (AD) brain.
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Donepezil is a potent and selective acetylcholinesterase (AChE) inhibitor developed for the treatment of Alzheimer's disease.
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After incubation of rat cortical cell cultures with the human immunodeficiency virus type 1 (HIV-1) coat protein gp120 for 12 h, cells showed fragmentation of DNA at internucleosomal linkers, the characteristic feature of apoptosis.