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pre-analytical
3 studies tagged pre-analytical, dated 2017-01-01 to 2024-05-30. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Effect of blood collection tube containing protease inhibitors on the pre-analytical stability of Alzheimer's disease plasma biomarkers 2024-05-30
- Effects of certain pre-analytical factors on the performance of plasma phospho-tau217 2024-02-08
- Cerebrospinal Fluid Aβ42/Aβ40 as a Means to Limiting Tube- and Storage-Dependent Pre-Analytical Variability in Clinical Setting 2017-01-01
Studies
3 studies carry this tag.
Date range
2017 to 2024
Top journals
- Alzheimer's research & therapy 1
- Journal of Alzheimer's disease : JAD 1
- Journal of neurochemistry 1
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The reliability of plasma biomarkers of Alzheimer's disease (AD) can be compromised by protease-induced degradation.
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Centrifugation improved the performance of plasma p-tau217, but thawing temperatures and up to three freeze-thaw cycles did not have a significant impact.
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The use of Aβ42/Aβ40 ratio rather than Aβ42 alone could contribute toward pre-analytical standardization, thus allowing the general use of CSF AD biomarkers in routine practice.