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Home › Research › Topics › nicotinic-acetylcholine

nicotinic-acetylcholine

6 studies tagged nicotinic-acetylcholine, dated 2003-05-06 to 2012-02-17. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology 2012-02-17
  2. The allosteric potentiation of nicotinic acetylcholine receptors by galantamine ameliorates the cognitive dysfunction in beta amyloid25-35 i.c.v.-injected mice: involvement of dopaminergic systems 2006-11-29
  3. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade 2006-06-08

Studies

6 studies carry this tag.

Date range

2003 to 2012

Top journals

  • Neuropharmacology 2
  • The Journal of pharmacology and experimental therapeutics 2
  • International journal of molecular sciences 1
  • Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. International journal of molecular sciences 2012-02-17 Treatments

    Alpha7 nicotinic acetylcholine receptor (α7 nAChR) is an important part of the cholinergic nerve system in the brain.

  2. The allosteric potentiation of nicotinic acetylcholine receptors by galantamine ameliorates the cognitive dysfunction in beta amyloid25-35 i.c.v.-injected mice: involvement of dopaminergic systems

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006-11-29 Treatments

    Galantamine, a drug for Alzheimer's disease, is a novel cholinergic agent with a dual mode of action, which inhibits acetylcholinesterase and allosterically modulates nicotinic acetylcholine receptors (nAChRs), as a result stimulates catecholamine neurotransmission.

  3. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropharmacology 2006-06-08 Treatments

    We show here that donepezil, galanathamine and tacrine, therapeutic acetylcholinesterase inhibitors currently being used for treatment of Alzheimer's disease, protect neuronal cells in a time- and concentration-dependent manner from glutamate neurotoxicity that involves apoptosis.

  4. Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of pharmacology and experimental therapeutics 2004-11-02 Treatments

    The N-methyl-d-aspartate (NMDA) receptor antagonist memantine is an approved drug for treatment of Alzheimer's disease (AD).

  5. Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropharmacology 2004-01-01 Treatments

    Galantamine is currently used to treat Alzheimer's disease patients; it behaves as a mild blocker of acetylcholinesterase (AChE) and has an allosteric modulating action on nicotinic acetylcholine receptors (nAChRs).

  6. Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of pharmacology and experimental therapeutics 2003-05-06 Treatments

    Donepezil is a potent and selective acetylcholinesterase (AChE) inhibitor developed for the treatment of Alzheimer's disease.

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