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Newest in this topic

  1. Evidence that the perinatal maternal microbiome mediates metabolite signaling programs that drive sex-specific microglial metabolic alterations and Alzheimer’s disease susceptibility 2026-10-23
  2. Change in gut microbiome precedes symptomatic Alzheimer’s disease and is correlated with amyloid-beta accumulation in the brain 2026-10-19
  3. The microbial soy metabolite S-equol mitigates cadmium neurotoxicity in mice 2026-10-06

Studies

173 studies carry this tag.

Date range

1998 to 2026

Top journals

  • Journal of Alzheimer's disease : JAD 13
  • Scientific reports 8
  • Molecular neurobiology 5
  • bioRxiv 5
  • Aging 4

104 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Anti-Alzheimer Properties of Probiotic, Lactobacillus plantarum MTCC 1325 in Alzheimer's Disease induced Albino Rats

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of clinical and diagnostic research : JCDR 2017-08-01 Disease mechanisms

    The study revealed that, L. plantarum MTCC1325 might have anti-Alzheimer properties against D-Galactose induced Alzheimer's disease.

  2. Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in cellular and infection microbiology 2017-07-11 Disease mechanisms

    Although the potential contribution of the human gastrointestinal (GI) tract microbiome to human health, aging, and disease is becoming increasingly acknowledged, the molecular mechanics and signaling pathways of just how this is accomplished is not well-understood.

  3. Intestinal microbial dysbiosis aggravates the progression of Alzheimer's disease in Drosophila

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Nature communications 2017-06-20 Disease mechanisms

    Neuroinflammation caused by local deposits of Aβ 42 in the brain is key for the pathogenesis and progression of Alzheimer's disease.

  4. Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific reports 2017-05-25 Disease mechanisms

    Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through the highly interconnected gut-brain axis.

  5. Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific reports 2017-02-08 Disease mechanisms

    Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder.

  6. Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Disease mechanisms

    The regulation of physiological gut functions such as peristalsis or secretion of digestive enzymes by the central nervous system via the Nervus vagus is well known.

  7. Altered Gut Microbiota in a Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Disease mechanisms

    The topic of gut microbiota is currently attracting considerable interest as a potential factor in Alzheimer's disease (AD).

  8. Alzheimer's Disease Histological and Behavioral Manifestations in Transgenic Mice Correlate with Specific Gut Microbiome State

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Disease mechanisms

    Alzheimer's disease (AD) is a neurodegenerative brain disease and is the most common form of dementia.

  9. Human gut microbiota: the links with dementia development

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Protein & cell 2016-11-19 Disease mechanisms

    Dementia is a comprehensive category of brain diseases that is great enough to affect a person's daily functioning.

  10. Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Frontiers in aging neuroscience 2016-11-10 Clinical trials

    Alzheimer's disease (AD) is associated with severe cognitive impairments as well as some metabolic defects.

  11. Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nutrition reviews 2016-10-01 Prevention and risk

    It has been hypothesized that alterations in the composition of the gut microbiota might be associated with the onset of certain human pathologies, such as Alzheimer disease, a neurodegenerative syndrome associated with cerebral accumulation of amyloid-β fibrils.

  12. Bacteroides fragilis Lipopolysaccharide and Inflammatory Signaling in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in microbiology 2016-09-26 Disease mechanisms

    The human microbiome consists of ~3.8 × 10 13 symbiotic microorganisms that form a highly complex and dynamic ecosystem: the gastrointestinal (GI) tract constitutes the largest repository of the human microbiome by far, and its impact on human neurological health and disease is becoming increasingly appreciated.

  13. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurobiology of aging 2016-08-31 Inflammation and the immune system

    Amy+ patients showed higher levels of pro-inflammatory cytokines (IL-6, CXCL2, NLRP3, and IL-1β) compared with both controls and with Amy- patients.

  14. From focal sepsis to periodontal medicine: a century of exploring the role of the oral microbiome in systemic disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The Journal of physiology 2016-08-28 Disease mechanisms

    The oral microbiome is established within a few minutes after birth and consists of stable multi-species communities that engage in a dynamic equilibrium with the host immune system.

  15. Alzheimer's disease and gut microbiota

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Science China. Life sciences 2016-08-26 Disease mechanisms

    Alzheimer's disease (AD) is a most common neurodegenerative disorder, which associates with impaired cognition.

  16. Towards understanding brain-gut-microbiome connections in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC systems biology 2016-08-26 Risk factors

    Employing an integrated computational approach, we provide intriguing and supporting evidence for a role of microbial metabolites, an important modifiable environmental factor, in AD etiology.

  17. Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Scientific reports 2016-07-21 Disease mechanisms

    Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features of Alzheimer's disease (AD).

  18. Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BioMed research international 2015-10-07 Disease mechanisms

    Probiotics actively participate in neuropsychiatric disorders.

  19. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Molecular nutrition & food research 2015-04-27 Disease mechanisms

    Scope Grape seed polyphenol extract (GSPE) is receiving increasing attention for its potential preventative and therapeutic roles in Alzheimer's disease (AD) and other age-related neurodegenerative disorders.

  20. Mechanisms of molecular mimicry involving the microbiota in neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2015-01-01 Genetics

    The concept of molecular mimicry was established to explain commonalities of structure which developed in response to evolutionary pressures.

  21. The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2015-01-01 Disease mechanisms

    This review, gathered from diverse sources, shows how our microbiome influences health and ultimately how well we age.

  22. Serum IgG antibody levels to periodontal microbiota are associated with incident Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. PloS one 2014-12-18 Disease mechanisms

    Serum IgG levels to common periodontal microbiota are associated with risk for developing incident AD.

  23. Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research 1998-01-01 Biomarkers

    Inflammatory processes may play a critical role in the pathogenesis of the degenerative changes and cognitive impairments associated with Alzheimer's disease (AD).

From across this tag

9 of the 173 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts