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late-life-depression-as-prodrome
4 studies tagged late-life-depression-as-prodrome, dated 2017-07-01 to 2025-09-25. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Risk factor analysis of cognitive frailty in older adults with type 2 diabetes mellitus: a cross-sectional study 2025-09-25
- Distinctive Progression Patterns of Brain Structural Damage Aid Classification of Frontotemporal Dementia Variants 2025-09-01
- Late Life Depression is Not Associated With Alzheimer-Type Tau: Preliminary Evidence From a Next-Generation Tau Ligand PET-MR Study 2024-07-18
Studies
4 studies carry this tag.
Date range
2017 to 2025
Top journals
- European Journal of Neurology 1
- Frontiers in Aging Neuroscience 1
- JAMA psychiatry 1
- The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 1
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The prevalence of CF was 24.3%. Cerebrovascular disease (OR: 2.39, 95% CI: 1.44-3.97) and peripheral arterial disease (OR: 1.74, 95% CI: 1.03-2.95) were significant risk factors, while higher education (OR 0.85, 95% CI 0.76-0.94) and later diabetes onset (OR: 0.93, 95% CI: 0.88-0.98) were protective.
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At baseline, sbvFTD showed right-predominant temporal pole involvement associated with significant right frontal atrophy.
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Our findings suggest AD-type tau is not higher in LLD compared to non-depressed, cognitively unimpaired older adults and appears unlikely to contribute to lower gray matter volume in LLD, further underscoring the need to distinguish major depressive disorder from depressive symptoms occurring in early AD.
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Those reporting depressive symptoms in 1985 (mean follow-up, 27 years) did not have significantly increased risk for dementia (hazard ratio [HR], 1.21; 95% CI, 0.95-1.54) in Cox regression adjusted for sociodemographic covariates, health behaviors, and chronic conditions.