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Home › Research › Topics › dna-methylation

dna-methylation

17 studies tagged dna-methylation, dated 2004-05-01 to 2022-10-31. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. The DNA Methylation in Neurological Diseases 2022-10-31
  2. Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease 2020-11-30
  3. Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease 2019-03-21

Studies

17 studies carry this tag.

Date range

2004 to 2022

Top journals

  • Alzheimer's & dementia : the journal of the Alzheimer's Association 2
  • Brain, behavior, and immunity 2
  • Acta neuropathologica 1
  • Alzheimer's & dementia (Amsterdam, Netherlands) 1
  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 1

15 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The DNA Methylation in Neurological Diseases

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cells 2022-10-31 Genetics

    DNA methylation is critical for the normal development and functioning of the human brain, such as the proliferation and differentiation of neural stem cells, synaptic plasticity, neuronal reparation, learning, and memory.

  2. Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Nature communications 2020-11-30 Genetics

    DNA methylation differences in Alzheimer's disease (AD) have been reported.

  3. Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Clinical epigenetics 2019-03-21 Genetics

    Our study represents the first epigenome-wide association study of both DNA methylation and hydroxymethylation in Alzheimer's disease entorhinal cortex.

  4. Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Acta neuropathologica 2019-02-02 Genetics

    Late-onset Alzheimer's disease (AD) is a complex age-related neurodegenerative disorder that likely involves epigenetic factors.

  5. DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Epigenetics & chromatin 2018-07-25 Genetics

    Our data highlight the complex interplay between disease, age and cell-type-specific methylation changes in AD risk genes thus offering new perspectives for the validation and interpretation of large EWAS results.

  6. Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2018-06-21 Genetics

    Associations are present between environmental risk factors for AD and age acceleration.

  7. DNA Methyltransferases, DNA Methylation, and Age-Associated Cognitive Function

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2018-04-28 Genetics

    Ageing, a leading cause of the decline/deficits in human learning, memory, and cognitive abilities, is a major risk factor for age-associated neurodegenerative disorders such as Alzheimer’s disease.

  8. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2018-03-15 Genetics

    We present robust evidence for elevated DNA methylation associated with Alzheimer's disease neuropathology spanning the HOXA gene cluster on chromosome 7.

  9. Epigenetic Pathways in Human Disease: The Impact of DNA Methylation on Stress-Related Pathogenesis and Current Challenges in Biomarker Development

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. EBioMedicine 2017-04-04 Genetics

    HPA axis genes implicated in glucocorticoid regulation play an important role in regulating the physiological impact of social and environmental stress, and have become a focal point for investigating the role of glucocorticoid regulation in the etiology of disease.

  10. Epigenetics in Alzheimer's Disease: Perspective of DNA Methylation

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Molecular neurobiology 2017-01-14 Genetics

    Research over the years has shown that causes of Alzheimer's disease are not well understood, but over the past years, the involvement of epigenetic mechanisms in the developing memory formation either under pathological or physiological conditions has become clear.

  11. Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2016-11-22 Genetics

    Our results indicate that cycles of DNA methylation contribute to the regulation of BMAL1 rhythms in the brain.

  12. Global changes in DNA methylation in Alzheimer's disease peripheral blood mononuclear cells

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Brain, behavior, and immunity 2014-11-13 Genetics

    Changes in epigenetic marks may help explain the late onset of Alzheimer's disease (AD).

  13. DNA methylation, a hand behind neurodegenerative diseases

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in aging neuroscience 2013-12-05 Genetics

    Epigenetic alterations represent a sort of functional modifications related to the genome that are not responsible for changes in the nucleotide sequence.

  14. DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Brain : a journal of neurology 2013-09-11 Genetics

    The central nervous system has a pattern of gene expression that is closely regulated with respect to functional and anatomical regions.

  15. Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Alzheimer's disease : JAD 2012-01-01 Genetics

    Evidence supports a role for epigenetic mechanisms in the pathogenesis of late-onset Alzheimer's disease (LOAD), but little has been done on a genome-wide scale to identify potential sites involved in disease.

  16. DNA methylation in repetitive elements and Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain, behavior, and immunity 2011-02-03 Genetics

    Epigenetics is believed to play a role in Alzheimer's disease (AD).

  17. Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004-05-01 Genetics

    Fine-tuning of neuronal connections during development is regulated through environmental interactions.

All topic tags with their study counts