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dephosphorylation
2 studies tagged dephosphorylation, dated 1996-03-01 to 1999-10-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Androgens Prevent the Heat Shock-Induced Hyperphosphorylation but not Dephosphorylation of t in Female Rats. Implications for Alzheimer's Disease 1999-10-01
- Heat shock induces rapid dephosphorylation of tau in both female and male rats followed by hyperphosphorylation only in female rats: implications for Alzheimer's disease 1996-03-01
Studies
2 studies carry this tag.
Date range
1996 to 1999
Top journals
- Journal of Alzheimer's disease : JAD 1
- Journal of neurochemistry 1
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We have previously shown that heat shock induces rapid dephosphorylation of tau in both female and male rats followed by hyperphosphorylation only in female rats (J Neurochem 66 (1996), 1140-1149).
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Female and male 2-3-month-old Sprague-Dawley rats were heat shocked at 42 degrees C for 15 min. At 0, 3, 6, 12 and 24 h after heat shock, qualitative and quantitative immunoblot analysis of cerebral extracts and immunohistochemistry were performed using monoclonal anti-tau antibodies that recognize nonphosphorylated (Tau-1), phosphorylated (PHF-1), and phosphate-independent (Tau-5 and Tau-46) epitopes.