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csf-biomarkers
9 studies tagged csf-biomarkers, dated 2015-02-25 to 2024-04-03. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly 2024-04-03
- Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition 2024-01-12
- Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive decline 2023-06-13
Studies
9 studies carry this tag.
Date range
2015 to 2024
Top journals
- Neurology 2
- Alzheimer's & dementia (Amsterdam, Netherlands) 1
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Alzheimer's research & therapy 1
- Brain communications 1
8 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The immune system substantially influences age-related cognitive decline and Alzheimer's disease (AD) progression, affected by genetic and environmental factors.
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Neuroinflammation is a hallmark of Alzheimer's disease (AD) and both positive and negative associations of individual inflammation-related markers with brain structure and cognitive function have been described.
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64/100
Relative to controls, greater Alzheimer's disease pathology (lower amyloid-β 42 /amyloid-β 40 , higher phosphorylated-tau-181) and synaptic degeneration (neurogranin) biomarker concentrations were associated with more adverse white matter metrics (e.g. lower neurite density, higher mean diffusivity) in patients with asthma.
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Plasma and CSF AD biomarkers may perform similarly across diverse populations but future studies in large, diverse cohorts are needed.
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Clinical trials testing tau-targeting therapies may benefit from using fluid biomarkers to recruit individuals at risk of tau aggregation.
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We conclude that NPTX2 is a promising synapse-derived disease progression biomarker in genetic FTD.
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51/100
NDs share a CSF profile characterized by increased levels of CSF CHIT1, YKL-40, and GFAP, which likely reflects a common neuroinflammatory response to protein misfolding and aggregation.
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CSF biomarkers of angiogenesis are increased in PD, and they are associated with gait difficulties, BBB dysfunction, WMLs, and CMB.
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In MCI, specific aspects of SCD severity and quality are related to CSF biomarkers indicative of AD.