Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly 2024-04-03
  2. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition 2024-01-12
  3. Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive decline 2023-06-13

Studies

9 studies carry this tag.

Date range

2015 to 2024

Top journals

  • Neurology 2
  • Alzheimer's & dementia (Amsterdam, Netherlands) 1
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Alzheimer's research & therapy 1
  • Brain communications 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Science advances 2024-04-03 Biomarkers

    The immune system substantially influences age-related cognitive decline and Alzheimer's disease (AD) progression, affected by genetic and environmental factors.

  2. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Molecular psychiatry 2024-01-12 Biomarkers

    Neuroinflammation is a hallmark of Alzheimer's disease (AD) and both positive and negative associations of individual inflammation-related markers with brain structure and cognitive function have been described.

  3. Impact of asthma on the brain: evidence from diffusion MRI, CSF biomarkers and cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Brain communications 2023-06-13 Biomarkers

    Relative to controls, greater Alzheimer's disease pathology (lower amyloid-β 42 /amyloid-β 40 , higher phosphorylated-tau-181) and synaptic degeneration (neurogranin) biomarker concentrations were associated with more adverse white matter metrics (e.g. lower neurite density, higher mean diffusivity) in patients with asthma.

  4. Comparison of plasma and CSF biomarkers across ethnoracial groups in the ADNI

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2022-05-01 Biomarkers

    Plasma and CSF AD biomarkers may perform similarly across diverse populations but future studies in large, diverse cohorts are needed.

  5. CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial design

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2022-02-28 Biomarkers

    Clinical trials testing tau-targeting therapies may benefit from using fluid biomarkers to recruit individuals at risk of tau aggregation.

  6. Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Journal of neurology, neurosurgery, and psychiatry 2020-04-09 Biomarkers

    We conclude that NPTX2 is a promising synapse-derived disease progression biomarker in genetic FTD.

  7. CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's research & therapy 2019-12-31 Biomarkers

    NDs share a CSF profile characterized by increased levels of CSF CHIT1, YKL-40, and GFAP, which likely reflects a common neuroinflammatory response to protein misfolding and aggregation.

  8. Increased CSF biomarkers of angiogenesis in Parkinson disease

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Neurology 2015-10-28 Biomarkers

    CSF biomarkers of angiogenesis are increased in PD, and they are associated with gait difficulties, BBB dysfunction, WMLs, and CMB.

  9. Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2015-02-25 Biomarkers

    In MCI, specific aspects of SCD severity and quality are related to CSF biomarkers indicative of AD.

All topic tags with their study counts