alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Home › Research › Topics › clinically-normal

clinically-normal

3 studies tagged clinically-normal, dated 2019-10-01 to 2023-11-08. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults 2023-11-08
  2. Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults 2020-06-05
  3. Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults 2019-10-01

Studies

3 studies carry this tag.

Date range

2019 to 2023

Top journals

  • JAMA neurology 1
  • NeuroImage 1
  • Neurology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Neurology 2023-11-08 Brain scans and imaging

    In older adults, longitudinal hippocampal atrophy is associated with cognitive decline, independently of Aβ or tau, suggesting that non-AD pathologies (e.g., TDP-43, vascular) may contribute to hippocampal-mediated cognitive decline.

  2. Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. NeuroImage 2020-06-05 Brain scans and imaging

    Neurofibrillary tau tangles are a hallmark pathology of Alzheimer's disease (AD) and are more closely associated with AD-related cortical atrophy and symptom severity than amyloid-beta (Aβ).

  3. Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. JAMA neurology 2019-10-01 Brain scans and imaging

    In models examining PACC decline and volume loss, there was a significant interaction of physical activity with Aβ burden, such that greater physical activity was associated with slower Aβ-related cognitive decline (β, 0.03; 95% CI, 0.02-0.05; P < .001) and volume loss (β, 482.07; 95% CI, 189.40-774.74; P = .002).

All topic tags with their study counts