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Interventions for preventing delirium in hospitalised patients
Siddiqi N, Stockdale R, Britton AM, Holmes J.. The Cochrane database of systematic reviews, 2007-04-18
Topic: Risk, prevention and care in population studies
It is associated with increases in mortality, physical morbidity, length of hospital stay, institutionalisation and costs to healthcare providers. Main results Six studies with a total of 833 participants were identified for inclusion. In logistic regression analyses adjusting for pre fracture dementia and Activities of Daily Living impairment, there was no reduction in effect size, OR 0.6, but this no longer remained significant [95% CI 0.3,1.3]. There was also no significant difference in cumulative delirium incidence between treatment and control groups in a sub-group of 50 patients with dementia (RR 0.9 [95% CI 0.59, 1.36]).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Siddiqi, N., Stockdale, R., Britton, A. M., & Holmes, J. (2007). Interventions for preventing delirium in hospitalised patients. The Cochrane database of systematic reviews. https://doi.org/10.1002/14651858.cd005563.pub2
Vancouver
Siddiqi N, Stockdale R, Britton AM, Holmes J. Interventions for preventing delirium in hospitalised patients. The Cochrane database of systematic reviews. 2007. doi:10.1002/14651858.cd005563.pub2. PMID: 17443600.
BibTeX
@article{siddiqi2007-17443600,
author = {Siddiqi, N. and Stockdale, R. and Britton, A. M. and Holmes, J.},
title = {{Interventions for preventing delirium in hospitalised patients}},
journal = {The Cochrane database of systematic reviews},
year = {2007},
doi = {10.1002/14651858.cd005563.pub2},
pmid = {17443600},
url = {https://doi.org/10.1002/14651858.cd005563.pub2}
}
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Key findings
- It is associated with increases in mortality, physical morbidity, length of hospital stay, institutionalisation and costs to healthcare providers.
- Main results Six studies with a total of 833 participants were identified for inclusion.
- In logistic regression analyses adjusting for pre fracture dementia and Activities of Daily Living impairment, there was no reduction in effect size, OR 0.6, but this no longer remained significant [95% CI 0.3,1.3].
- There was also no significant difference in cumulative delirium incidence between treatment and control groups in a sub-group of 50 patients with dementia (RR 0.9 [95% CI 0.59, 1.36]).
Why it matters
In six studies with 833 participants, interventions for preventing delirium in hospitalised patients did not show a significant reduction in delirium after adjusting for pre-fracture dementia and Activities of Daily Living impairment. There was also no significant difference in delirium incidence in a subgroup of 50 patients with dementia.
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Study details
- Participants833
- Effect sizeOR 0.48; RR 0.64; OR 0.6
- Evidence strengthHigh
How this study scored 69/100
Published in a leading specialty journal, and it is a systematic review of all the studies on the question. We have no data on impact for its field and year, so that was left out: it earned 65 of the 94 points we could judge it on, which is 69 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (The Cochrane database of systematic reviews) |
| Journal's citation record | 3 / 4 | Cochrane Database of Systematic Reviews: journal h-index 468 (OpenAlex, 2026-10-29) |
| Study design | 12 / 12 | A systematic review of all the studies on the question (from PubMed type “Systematic Review”) |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2007 — within 20 year(s) of the newest study here |
| Sample size | 2 / 4 | 833 participants |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | A review of other studies — randomisation is not credited here |
| Times cited | 5 / 7 | Cited 280 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 13.3 citations a year over 21 year(s) since 2007 |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | 1 / 6 | Cited by 2 other studies in this library |
| Still being cited | 1 / 4 | Cited 7 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author John Holmes: h-index 54 (OpenAlex, whole career) |
| Institution's track record | 1 / 3 | University of Leeds: institution h-index 950 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 17443600) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 65 / 94 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 65 of the 94 points we could judge it on is 69 out of 100. |
| Total | 69 / 100 | — |
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