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Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers
Alison R Anderson, Juliana Souza-Talarico, Ishika Mahajan, Todd B Monroe, Alai Tan, Amy R Mackos, Jodi L Ford, Kathy D Wright et al.. Pain management nursing : official journal of the American Society of Pain Management Nurses, 2024-12-04
Topic: Health services, long-term care and technology
Contrary to expectations, pain and mental health measures for PLWAD displayed a trend toward negative correlation with their hair cortisol levels. Conversely, caregiver pain and mental health measures had a trend toward positive correlation with their hair cortisol levels. There was also a trend that higher pain in PLWAD was associated with higher caregiver burden. This exploratory pilot study showed associational trends suggesting a complex relationship between pain, mental health, and stress in PLWAD-caregiver dyads. This preliminary work will inform future studies that can help advance targeted, tailored interventions.
Key findings
- Contrary to expectations, pain and mental health measures for PLWAD displayed a trend toward negative correlation with their hair cortisol levels.
- Conversely, caregiver pain and mental health measures had a trend toward positive correlation with their hair cortisol levels.
- There was also a trend that higher pain in PLWAD was associated with higher caregiver burden.
- This exploratory pilot study showed associational trends suggesting a complex relationship between pain, mental health, and stress in PLWAD-caregiver dyads.
- This preliminary work will inform future studies that can help advance targeted, tailored interventions.
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Study details
- Evidence strengthLow
How this study scored 43/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 24 of the 56 points we could judge it on, which is 43 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Pain management nursing : official journal of the American Society of Pain Management Nurses) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 39632151) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 24 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 24 of the 56 points we could judge it on is 43 out of 100. |
| Total | 43 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Anderson, A. R., Souza-Talarico, J., Mahajan, I., Monroe, T. B., Tan, A., Mackos, A. R., et al. (2025). Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers. Pain management nursing : official journal of the American Society of Pain Management Nurses. https://doi.org/10.1016/j.pmn.2024.10.010
Vancouver
Anderson AR, Souza-Talarico J, Mahajan I, Monroe TB, Tan A, Mackos AR, et al. Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers. Pain management nursing : official journal of the American Society of Pain Management Nurses. 2025. doi:10.1016/j.pmn.2024.10.010. PMID: 39632151.
BibTeX
@article{anderson2025-39632151,
author = {Anderson, Alison R and Souza-Talarico, Juliana and Mahajan, Ishika and Monroe, Todd B and Tan, Alai and Mackos, Amy R and Ford, Jodi L and Wright, Kathy D and others},
title = {{Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers}},
journal = {Pain management nursing : official journal of the American Society of Pain Management Nurses},
year = {2025},
doi = {10.1016/j.pmn.2024.10.010},
pmid = {39632151},
url = {https://doi.org/10.1016/j.pmn.2024.10.010}
}
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