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Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates
Huitong Ding, Minzae Kim, Edward Searls, Preeti Sunderaraman, Ileana De Anda-Duran, Spencer Low, Zachary Popp, Phillip H Hwang et al.. Frontiers in neurology, 2024-02-15
Topic: Brain imaging, connectivity and assessment
Age- and sex-specific reference values were generated for three DANA tasks. Participants below 60 had median response times for the Go-No-Go task of 796 ms (men) and 823 ms (women), with age-related increases in both sexes. Validation cohort results mostly aligned with these references. Different tasks showed unique clinical correlations. For instance, response time in the Code Substitution task correlated positively with total cholesterol and diabetes, but negatively with high-density lipoprotein and low-density lipoprotein cholesterol levels, and triglycerides. This study established and validated reference values for digital neuropsychological measures of DANA in cognitively intact white participants, potentially improving their use in future clinical studies and practice.
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APA 7th
Ding, H., Kim, M., Searls, E., Sunderaraman, P., De Anda-Duran, I., Low, S., et al. (2024). Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates. Frontiers in neurology. https://doi.org/10.3389/fneur.2024.1340710
Vancouver
Ding H, Kim M, Searls E, Sunderaraman P, De Anda-Duran I, Low S, et al. Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates. Frontiers in neurology. 2024. doi:10.3389/fneur.2024.1340710. PMID: 38426173.
BibTeX
@article{ding2024-38426173,
author = {Ding, Huitong and Kim, Minzae and Searls, Edward and Sunderaraman, Preeti and De Anda-Duran, Ileana and Low, Spencer and Popp, Zachary and Hwang, Phillip H and others},
title = {{Digital neuropsychological measures by defense automated neurocognitive assessment: reference values and clinical correlates}},
journal = {Frontiers in neurology},
year = {2024},
doi = {10.3389/fneur.2024.1340710},
pmid = {38426173},
url = {https://doi.org/10.3389/fneur.2024.1340710}
}
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Key findings
- Age- and sex-specific reference values were generated for three DANA tasks.
- Participants below 60 had median response times for the Go-No-Go task of 796 ms (men) and 823 ms (women), with age-related increases in both sexes.
- Validation cohort results mostly aligned with these references.
- Different tasks showed unique clinical correlations.
- For instance, response time in the Code Substitution task correlated positively with total cholesterol and diabetes, but negatively with high-density lipoprotein and low-density lipoprotein cholesterol levels, and triglycerides.
Study details
- Participants932
- Evidence strengthModerate
How this study scored 55/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 31 of the 56 points we could judge it on, which is 55 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Frontiers in neurology) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2024 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 932 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38426173) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 31 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 31 of the 56 points we could judge it on is 55 out of 100. |
| Total | 55 / 100 | — |
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