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Home › Research › Vascular contributions

Central auditory dysfunction as a harbinger of Alzheimer dementia

Gates GA, Anderson ML, McCurry SM, Feeney MP, Larson EB.. Archives of otolaryngology--head & neck surgery, 2011-04-01

This page is alzhub.org's plain-English summary of a published study, not the paper itself. It is generated from the record we hold for this study, sourced and linked below — check the original for the full text and methods.

✓ Peer-reviewed alzhub usefulness score 52 out of 100. Vascular contributions

Topic: Amyloid, tau and blood-test diagnosis

Objective To confirm that central auditory dysfunction (CAD) may be a precursor to the onset of Alzheimer dementia (AD). Design Cohort study. Setting Research study center. Participants Two hundred seventy-four volunteers from a dementia surveillance cohort were followed up for as long as 4 years after undergoing complete audiometric assessment. Twenty-one received a consensus diagnosis of AD after a hearing test. Intervention The following 3 central auditory tests were performed: the Dichotic Sentence Identification, the Dichotic Digits, and the Synthetic Sentence Identification With Ipsilateral Competing Message. Main outcome measures A new diagnosis of AD using the National Institute of Neurological and Communicative Diseases and Stroke-Alzheimer Disease and Related Disorders Association criteria at a consensus conference. Results The mean scores on each CAD test were significantly poorer in the incident dementia group. Cox proportional hazards models with age as the time scale were used to estimate the hazard ratio for incident dementia based on CAD test results. After adjusting for educational level, the hazard ratio for incident dementia in people with severe CAD based on a Dichotic Sentence Identification in free report mode of less than 50% was 9.9 (95% confidence interval, 3.6-26.7). Conclusions Central auditory dysfunction is a precursor to AD. We recommend evaluation with CAD tests in older adults who report hearing difficulty. Those with severe CAD should receive a modified rehabilitation program and be considered for referral for neurologic evaluation.

Key findings

Study details

How this study scored 52/100
How this study's score is builtJournal tier 7 of 10; Journal's citation record left out, no data; Study design 7 of 12; Strength of evidence 3 of 5; Peer-review validation 10 of 10; How recent 1 of 5; Sample size 0 of 4; Effect reported 0 of 3; Studied in people 0 of 3; Randomised / blinded 0 of 2; Times cited left out, no data; Citations per year left out, no data; Impact for its field and year left out, no data; Cited by studies here left out, no data; Still being cited left out, no data; Senior author's track record left out, no data; Institution's track record left out, no data; Multi-centre collaboration left out, no data; Indexed in PubMed 2 of 2; Free to read 0 of 2. 30 of the 58 points it could be judged on, which is 52 of 100. Total 52 of 100.30 of the 58 points we could judge = 52 of 100

Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 30 of the 58 points we could judge it on, which is 52 out of 100.

ComponentPointsWhy
Journal tier 7 / 10 Tier 3 — peer-reviewed journal (Archives of otolaryngology--head & neck surgery)
Journal's citation record — / 4 No journal record from OpenAlex — left out of this score
Study design 7 / 12 A cohort study following people over time
Strength of evidence 3 / 5 Rated “moderate” in our summary
Peer-review validation 10 / 10 Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent 1 / 5 2011 — within 20 year(s) of the newest study here
Sample size 0 / 4 Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported 0 / 3 No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people 0 / 3 Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomised / blinded 0 / 2 No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited — / 7 No citation count (not found in OpenAlex) — left out of this score
Citations per year — / 5 No citation count or no year — left out of this score
Impact for its field and year — / 6 No field-weighted citation impact (OpenAlex has none yet) — left out of this score
Cited by studies here — / 6 Not yet checked against this library's citation graph — left out of this score
Still being cited — / 4 No yearly citation counts — left out of this score
Senior author's track record — / 4 Senior author's record not available — left out of this score
Institution's track record — / 3 No institution listed in OpenAlex — left out of this score
Multi-centre collaboration — / 3 Institutions not listed — left out of this score
Indexed in PubMed 2 / 2 Indexed in PubMed (PMID 21502479)
Free to read 0 / 2 Behind a paywall — scores zero
Points 30 / 58 Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 30 of the 58 points we could judge it on is 52 out of 100.
Total 52 / 100 —

What each of these 20 components measures, and what this score is not →

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Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.

APA 7th

Gates, G. A., Anderson, M. L., McCurry, S. M., Feeney, M. P., & Larson, E. B. (2011). Central auditory dysfunction as a harbinger of Alzheimer dementia. Archives of otolaryngology--head & neck surgery. https://doi.org/10.1001/archoto.2011.28

Vancouver

Gates GA, Anderson ML, McCurry SM, Feeney MP, Larson EB. Central auditory dysfunction as a harbinger of Alzheimer dementia. Archives of otolaryngology--head & neck surgery. 2011. doi:10.1001/archoto.2011.28. PMID: 21502479.

BibTeX

@article{gates2011-21502479,
  author  = {Gates, G. A. and Anderson, M. L. and McCurry, S. M. and Feeney, M. P. and Larson, E. B.},
  title   = {{Central auditory dysfunction as a harbinger of Alzheimer dementia}},
  journal = {Archives of otolaryngology--head \& neck surgery},
  year    = {2011},
  doi     = {10.1001/archoto.2011.28},
  pmid    = {21502479},
  url     = {https://doi.org/10.1001/archoto.2011.28}
}

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