Postoperative delirium (POD) is often under-recognized in clinical practice. 3 key findings →
Participants: 143 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Postoperative delirium (POD) is often under-recognized in clinical practice. 3 key findings →
Participants: 143 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
A total of 327 patients were included in this study. 5 key findings →
Design: cohort study Participants: 327 Evidence: moderate
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In a sample of 2,599 Medicare beneficiaries (mean age 78.4 years, 52.9% female, 81.8% White), we identified a total of 5,677 hospitalization claims. 5 key findings →
Participants: 5,677 Evidence: low
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A case-control GWAS was performed in the UK Biobank to identify genetic variants associated with postoperative delirium, adjusted for age, sex, genetic chip, and the first 10 principal components. 5 key findings →
Design: case-control study Evidence: moderate
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Delirium is a severe, acute neuropsychiatric syndrome that is highly prevalent in acute hospital populations. 4 key findings →
Participants: 1,885 Evidence: low
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Our findings support an association between neuroaxonal injury and delirium. 3 key findings →
Participants: 130 Evidence: low
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During a median follow-up of 13.8 years, 6554 (1.9%) cases of incident delirium were documented. 5 key findings →
Participants: 346,846 Evidence: low
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Of 75 221 admissions, 62 188 (82.7%; 33 625 unique patients; mean age 80.2 years; 55.8% female) had a 4AT on admission. 4 key findings →
Evidence: low
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Upon initiation of guanfacine, patients with delirium had a reduction in daily antipsychotic exposure and a decrease in positive delirium screens. 4 key findings →
Design: cohort study Participants: 56 Evidence: moderate
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PurposeDelirium is a common yet preventable complication of hospitalization, surgery and illness that is associated with poor outcomes. 1 key finding →
Design: cohort study Evidence: moderate
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Participating ICU in both surveys (2016: n = 559, 2024: n = 447) had similar basic characteristics and enabled comparison. 5 key findings →
Participants: 559 Evidence: low
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The studied cohort comprised 4601 patients, mean age of 83.93 years and 56.26% were women. 5 key findings →
Participants: 4,601 Evidence: moderate
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The risk of delirium admissions was elevated for the first 1-30 days of prescriptions [IRR 1.54 (95% CI 1.30-1.82) for men, 1.44 (1.22-1.70) for women] and whilst reducing over time for women [1.10 (0.94-1.29) for 91-365 days of prescriptions], it remained elevated for men [1.38 (1.17-1.64)]. 5 key findings →
Participants: 293 Evidence: low
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The incidence of POD was 8.2% (26 of 316). 5 key findings →
Participants: 316 Evidence: low
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Among 51,202 admissions (mean/SD age = 82/7 years), any cognitive morbidity was present in 18,225 (35.6%, 95% CI 35.2-36.0%): delirium occurred in 24.0% (n = 12,289, of which 14.3% (n = 7332) had delirium only and 9.7% (n = 4957) had delirium + dementia) dementia only in 8.7%, (n = 4450), AMTS <8 in 2.9% (n = 1486). 5 key findings →
Participants: 12,289 Evidence: low
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Delirium is an independent marker for increased mortality among older medical inpatients during the 12 months after hospital admission. 3 key findings →
Participants: 243 Evidence: low
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Using a structured instrument, 325 elderly patients admitted to a general hospital for an acute medical problem were evaluated daily in order to detect symptoms of delirium. 1 key finding →
Participants: 125 Evidence: low
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This risk prediction rule may help identify a group of individuals in the ED at high risk of developing delirium who should undergo screening, but it requires external validation. 2 key findings →
Participants: 700 Evidence: low
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The data suggest that instruments measuring delirium severity and psychomotor features provide important prognostic information and should be integrated into the assessment of delirium. 3 key findings →
Participants: 166 Evidence: low
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The authors analyze 133 cases of organic mental disorders (OMDs) from a total of 771 patients who were referred for psychiatric consultation from a general hospital. 4 key findings →
Participants: 771 Evidence: low
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Transient cognitive disorders (delirium and pseudodelirium) are highly prevalent among the elderly, especially those with brain damage. 5 key findings →
Evidence: low
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A total of 260,200 older adults were screened for delirium (median [IQR] age in years: 78.0 [74.0-84.0]; female: 143,402 [55.1%]; non-Hispanic Black: 40,737 [15.8%]; Hispanic: 30,760 [11.9%]; median [IQR] Area Deprivation Index: 4.0 [2.0-6.0]; median [IQR] Charlson Comorbidity Index: 10.0 [8.0-13.0]). 5 key findings →
Participants: 260,200 Evidence: low
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Systemic inflammatory biomarkers were primarily associated with age/socio-demographic characteristics, remained strikingly stable over time, and were not associated with AD progression. 5 key findings →
Participants: 333 Evidence: low
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Delirium is a common cause and complication of hospitalization in the elderly and is associated with higher risk of future dementia and progression of existing dementia, of which 70% is Alzheimer's disease (AD). 3 key findings →
Evidence: low
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Postoperative delirium (POD) is a common and severe neuropsychiatric complication affecting older adults after surgery. 1 key finding →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →