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Research

27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 1,026–1,050 of 1,428 studies scoring ≤ 29 out of 100 (page 42 of 58) · 27,780 in the whole library · How the 0–100 score works

Download bibliography of the first 500 of these studies, in this order: BibTeX (.bib) · RIS (.ris)

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 13,259 studies have no institution on record and are not counted here.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

From Dementia Prevention Literacy to Preventive Agency: A Proposed Theoretical Framework for Translating Knowledge into Action

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-10-20

Dementia prevention education increasingly seeks to translate evidence about modifiable risk factors into meaningful public engagement and preventive action. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

“The conversation wouldn’t happen without us”: How interpreter involvement affects dementia service delivery for CALD clients in Australia

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-10-16

Participants perceived that interpreter involvement could support communication, direct participation, and the interpretability of assessments when it was timely, appropriately prepared, and aligned with clinical roles. 1 key finding →

Design: cross-sectional Participants: 64 Evidence: low

Full summary, score breakdown and related studies → Original source

The Role and Future Potential of Radio, Podcasts, and YouTube in Influencing Awareness and Policy on Neurodegenerative Diseases in the Arab Gulf: A Focus on Oman, Qatar, UAE, and Saudi Arabia

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-10-14

The increasing prevalence of neurodegenerative diseases (NDs), especially Alzheimer's and Parkinson's, is a major public health concern in the Gulf countries (GCs) due to the rapid increase in life expectancy and population aging. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source

The influence of cognitive decline on the severity and quantity of drug-drug interactions

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-10-11

These findings indicate that cognitive impairment may mark a population vulnerable to medication complexity rather than independently driving DDI risk, with polypharmacy emerging as the principal modifiable determinant. 4 key findings →

Participants: 101 Evidence: low

Full summary, score breakdown and related studies → Original source

What Do Care Staff Know About Behavioural and Psychological Symptoms of Dementia? A Mixed- Methods Study in Long-Term Care

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-10-06

Mean scores were 23.45/30 (78.2%) for general Alzheimer’s disease knowledge and 13.75/18 (76.4%) for BPSD knowledge; the scores were moderately correlated (ρ = .598, p < .001). 3 key findings →

Design: cross-sectional Participants: 196 Evidence: low

Full summary, score breakdown and related studies → Original source

Volumetric Integrity of Frontotemporal and Perisylvian Regions for Predicting Behavioral and Language Impairment in Behavioral FTD: A Structural MRI Study

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-10-05

In this bvFTD cohort, structural volumes of key frontotemporal and perisylvian regions did not predict behavioral or language impairments after correction for multiple comparisons. 3 key findings →

Design: longitudinal study Participants: 87 Evidence: moderate

Full summary, score breakdown and related studies → Original source

Shared and Divergent Multisensory Emotion Perception Deficits across Mild Cognitive Impairment, Alzheimer’s Disease, and Frontotemporal Dementia: A Systematic Review and Hierarchical Bayesian Meta-Analysis

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. PsyArXiv 2026-10-01

The ability to decode others’ emotions from multisensory cues is central to social functioning. 3 key findings →

Design: systematic review Participants: 1,511 Evidence: high

Full summary, score breakdown and related studies → Original source

Network Localization of Anxiety as an Early Manifestation of Alzheimer’s Disease-related Neurodegeneration

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2026-10-26

Anxiety localizes to a brain circuit resembling the AD-related atrophy network, is consistent across the AD continuum and may extend beyond AD. 5 key findings →

Design: longitudinal study Participants: 1,775 Evidence: moderate

Full summary, score breakdown and related studies → Original source

Proteomic Signatures of Vulnerability Across Late-Life Depression, Frailty, and Neurodegeneration

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-10-20

Late-life depression (LLD) is increasingly recognized as a complex multisystem disorder associated with accelerated biological aging, impaired physiological resilience, frailty, and an increased risk of cognitive decline and dementia. 3 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

The Role of Cortisol in CNS Disease –11β-HSD1 Inhibition as a Potential New Therapeutic Strategy for Alzheimer’s Disease and Major Depressive Disorder

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-10-16

Cortisol is primarily synthesized by the adrenal glands, but also within specific tissues via a distinct enzymatic pathway. 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyses the synthesis of cortisol within cells to create local higher cortisol environments in those organs where it is highly expressed such as the liver and brain. 4 key findings →

Participants: 247 Evidence: low

Full summary, score breakdown and related studies → Original source

Beyond Usual Pace: Quick Walking Speed and Brain Health Outcomes in the Framingham Heart Study

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-10-15

We estimated associations per SD slower walking or smaller adaptability using linear, logistic, and Cox regression (10-year follow-up), overall and in women and men. 5 key findings →

Design: cross-sectional Participants: 2,308 Evidence: moderate

Full summary, score breakdown and related studies → Original source

Caregiving experiences of older-adult informal family caregivers for older adults with comorbid dementia and physical disability: A qualitative study using the caregiving stress-process model

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-10-14

Five core themes and fifteen corresponding sub-themes were extracted from interview transcripts: (1) Structural caregiving context, including family structural constraints, the influence of filial piety culture, and insufficient aged-care supply; (2) Multiple caregiving stressors, covering primary care burden, independent care decision-making pressure, restricted social engagement, and intra-family conflicts; (3) Limited buffering support resources, involving inadequate formal care services, insufficient informal assistance from relatives, and individual psychological coping strategies; (4) Negative caregiving experiences, including persistent physical exhaustion and sustained emotional depletion; (5) Dual perceptions of caregiving outcomes, consisting of emotional gains from kinship bonding, resistance to institutional care, and long-term anxiety about future care arrangements. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source

Alignment with sex-typical brain architecture: Links to mood pathology, sex hormones and transcriptomics of neurodegenerative conditions

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2026-10-02

We tested whether, across sexes, alignment with female-typical, rather than male-typical, patterns of neural functional connectivity (FC) would relate to a diagnosis (adolescent sample) or severity of symptoms (adult sample) associated with internalizing disorders, which tend to be more often diagnosed in females. 2 key findings →

Design: longitudinal study Evidence: moderate

Full summary, score breakdown and related studies → Original source

An explainable multimodal framework for exploring depression-associated speech representations in Alzheimer’s disease

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. medRxiv 2026-10-01

By comparing these unsupervised representations to a depression-labelled source corpus, one cluster demonstrated mathematical proximity (measured via cosine similarity in a shared latent space) to the source depression centroid. 3 key findings →

Design: longitudinal study Evidence: moderate

Full summary, score breakdown and related studies → Original source

Newly diagnosed postoperative depression and incident dementia after major surgery: a Korean nationwide retrospective cohort study

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-09-30

Newly diagnosed postoperative depression was associated with increased dementia risk, particularly in patients aged < 65 years, supporting prospective evaluation as a potential marker of long-term cognitive risk. 4 key findings →

Design: cohort study Participants: 424,637 Evidence: moderate

Full summary, score breakdown and related studies → Original source

Early life social isolation primes flies for more rapid TDP-43 dependent neurodegeneration later in life

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2026-09-28

A key pathophysiological hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is loss of nuclear localization and abnormal cytoplasmic aggregation of TAR DNA-binding protein 43 (TDP-43). 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

Caregiver burden and mood changes among unpaid caregivers of older adults living with dementia

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Research Square 2026-09-25

Depressive and anxiety symptoms were more pronounced among caregivers with longer caregiving duration (p = 0.01; p = 0.001) and those living with the care recipient (p = 0.04; p = 0.02). 4 key findings →

Design: cross-sectional Evidence: low

Full summary, score breakdown and related studies → Original source

Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer's Disease: Overlapping Phenotypes and Associations

⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. Preprints.org 2026-09-14

Traumatic brain injury (TBI), chronic traumatic encephalopathy (CTE), and Alzheimer's disease (AD) share several neuropathophysiological mechanisms, including axonal injury, neuroinflammation, and abnormal protein aggregation, which may contribute to overlapping clinical manifestations. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed