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Research

27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 1–19 of 19 studies in Cortex; a journal devoted to the study of the nervous system and behavior · 27,380 in the whole library · How the 0–100 score works

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 12,859 studies have no institution on record and are not counted here.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Tau-PET imaging with [18F]AV-1451 in primary progressive apraxia of speech

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2018-01-02

Apraxia of speech is a motor speech disorder characterized by combinations of slow speaking rate, abnormal prosody, distorted sound substitutions, and trial-and-error articulatory movements. 1 key finding →

Design: cross-sectional Participants: 14 Evidence: low

Full summary, score breakdown and related studies → Original source

Alterations of the pulvinar in posterior cortical atrophy: A multimodal MRI study

✓ Peer-reviewed alzhub usefulness score 50 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2024-10-19

Cognitive and visual functions including visuospatial processing, visual perception, episodic memory, and naming were impaired among PCA patients. 5 key findings →

Participants: 29 Evidence: low

Full summary, score breakdown and related studies → Original source

Comprehension of insincere communication in neurodegenerative disease: lies, sarcasm, and theory of mind

✓ Peer-reviewed alzhub usefulness score 48 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2011-09-01

Comprehension of insincere communication is an important aspect of social cognition requiring visual perspective taking, emotion reading, and understanding others' thoughts, opinions, and intentions. 2 key findings →

Participants: 102 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Classification and clinicoradiologic features of primary progressive aphasia (PPA) and apraxia of speech

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2015-05-27

The consensus criteria for the diagnosis and classification of primary progressive aphasia (PPA) have served as an important tool in studying this group of disorders. 4 key findings →

Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Age of dementia diagnosis in community dwelling bilingual and monolingual Hispanic Americans

✓ Peer-reviewed alzhub usefulness score 45 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2014-12-19

Bilingualism has been reported to delay the age of retrospective report of first symptom in dementia. 4 key findings →

Participants: 1,789 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Machine learning approaches to diagnosis and laterality effects in semantic dementia discourse

✓ Peer-reviewed alzhub usefulness score 44 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2013-06-14

Advances in automatic text classification have been necessitated by the rapid increase in the availability of digital documents. 5 key findings →

Participants: 21 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Two insular regions are differentially involved in behavioral variant FTD and nonfluent/agrammatic variant PPA

✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2015-11-14

The non-fluent/agrammatic variant of primary progressive aphasia (nfvPPA) and the behavioral variant frontotemporal dementia (bvFTD) are focal neurodegenerative disorders belonging to the FTD-spectrum clinical syndromes. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Referential communication in Alzheimer's type dementia

✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2005-08-01

This paper investigates factors that underlie reduced informative content and lack of reference in the discourse of patients with Alzheimer's Type Dementia (DAT). 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Syntax, action verbs, action semantics, and object semantics in Parkinson's disease: Dissociability, progression, and executive influences

✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2015-06-03

Several studies have recently shown that basal ganglia (BG) deterioration leads to distinctive impairments in the domains of syntax, action verbs, and action semantics. 3 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Long-term declarative memory deficits in diffuse TBI: correlations with cortical thickness, white matter integrity and hippocampal volume

✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-03-08

We investigated structural brain damage in subjects who had suffered severe and diffuse traumatic brain injury (TBI), and examined its relationship with declarative memory impairment. 5 key findings →

Participants: 26 Evidence: low

Full summary, score breakdown and related studies → Original source

How to do things with (thousands of) words: Computational approaches to discourse analysis in Alzheimer's disease

✓ Peer-reviewed alzhub usefulness score 41 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2020-05-19

Natural Language Processing (NLP) is an ever-growing field of computational science that aims to model natural human language. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Default mode network differences between rigidity- and tremor-predominant Parkinson's disease

✓ Peer-reviewed alzhub usefulness score 38 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2016-05-06

There was decreased activity in the left inferior parietal cortex (IPC) and the left posterior cingulate cortex (PCC) within the DMN between PDAR and both HC and PDT subjects, even after controlling for multiple comparisons, but not between PDT and HC. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

Automated classification of primary progressive aphasia subtypes from narrative speech transcripts

✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-12-21

In the early stages of neurodegenerative disorders, individuals may exhibit a decline in language abilities that is difficult to quantify with standardized tests. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

Anosognosia in Alzheimer's disease: diagnosis, frequency, mechanism and clinical correlates

✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2014-12-01

Anosognosia is present in a large proportion of patients with mild Alzheimer's disease (AD), and its frequency increases with the progression of the illness. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

Abnormal network connectivity in frontotemporal dementia: evidence for prefrontal isolation

✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2012-09-24

The present findings support a theory of FTD as a disorder of frontolimbic disconnection leading to unconstrained prefrontal connectivity. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed