27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
In both phases, men were encouraged to visit their physician if the screen results indicated possible cognitive impairment. 3 key findings →
Design: cohort study Participants: 7,540 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Stigma negatively affects individuals with cognitive impairment and dementia. 5 key findings →
Design: systematic review Participants: 51 Evidence: high
Full summary, score breakdown and related studies → Original source
Recruitment ended in December 2014 with 16,703 Australian and 2,411 U.S. participants, a median age of 74 (range 65-98) years and 56% women. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Clinicians treating people with a hip fracture should be vigilant towards post-operative delirium if their patients are older, have pre-existing cognitive impairment and poorer overall general health. 4 key findings →
Participants: 6,704 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Overall, birth in an HSMS was associated with a 28% higher risk of dementia (adjusted hazard ratio [aHR], 1.28; 95% CI, 1.13-1.46) adjusted for age, sex, and race. 5 key findings →
Design: cohort study Participants: 7,423 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
However, in many low- and middle-income countries (LMIC) there is a lack of evaluation and the cross-cultural validity of SRH remains largely untested. 5 key findings →
Design: cohort study Participants: 16,940 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Roughly one in five hospice patients were discharged alive (21%; n = 1911). 2 key findings →
Design: cohort study Participants: 9,190 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Sample weights were used to ensure result generalizability. 5 key findings →
Design: cross-sectional Participants: 1,527 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Larger gains in rural adults' cognitive functioning between 2000 and 2010 that are linked with increased educational attainment demonstrate long-term public health benefits of investment in secondary education. 4 key findings →
Participants: 16,386 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Positive associations between self-efficacy and language did not significantly differ across race/ethnicity, although the bivariate association between self-efficacy and language was not significant among Hispanics. 5 key findings →
Design: cross-sectional Participants: 548 Evidence: moderate
Full summary, score breakdown and related studies → Original source
In this study, we report the experience of the only reference clinical next-generation sequencing lab in Saudi Arabia with the first 1000 families who span a wide-range of suspected Mendelian phenotypes. 1 key finding →
Participants: 1,019 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Non-linear associations between features of land use and cognitive impairment were confirmed in this new cohort of older people in England. 4 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Survival after dementia diagnosis differs by race/ethnicity, with shortest survival among whites and longest among Asian Americans. 3 key findings →
Participants: 23,032 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Poisson regression was used to model dementia incidence as a function of age, sex, educational level, race, and birth cohort, with profile likelihood used to identify the timing of significant increases or decreases in incidence. 3 key findings →
Participants: 1,348 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Numerous tools for assessment of cognitive impairment in low-literacy settings have been developed, and tools developed for use in high-income countries have also been validated in low-literacy settings. 2 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Prevalent hemodialysis patients demonstrate significant cognitive decline, particularly within tests of executive function. 5 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Variation in use of APMs in U.S. nursing homes based upon facility characteristics exemplifies the need for a more systematic protocol guiding the use of these medications, along with heightened regulatory policies and enforcement. 2 key findings →
Design: meta-analysis Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
BPSD are universally present, bear correlates with dementia type and severity, and cause significant caregiver distress. 2 key findings →
Design: cross-sectional Participants: 107 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The two overarching themes lend themselves to interventions at a service level and a community level which need to happen in synergy. 1 key finding →
Participants: 25,000 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Our results provide the first empirical evidence of CF in China. 5 key findings →
Participants: 5,708 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Our findings suggest that poor chewing ability is associated with cognitive impairment or dementia in the elderly living in rural area. 4 key findings →
Design: cross-sectional Participants: 295 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Goal 1 of the National Plan to Address Alzheimer's Disease is to prevent and effectively treat Alzheimer disease and Alzheimer disease-related dementias by 2025. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Higher arterial stiffness and pulsatility were associated with MCI and dementia in white participants. 3 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Amyloid-beta (Aβ) plays a key role in the pathogenesis of Alzheimer's disease (AD), but little is known about the proteoforms present in AD brain. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dementia prevalence estimates were higher than expected for this low-income rural community. 3 key findings →
Participants: 1,051 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →