27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
Our model could aid GPs or health service planners with the early detection of dementia. 1 key finding →
Design: case-control study Participants: 93,120 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
It shows no scale bias compared to SAGE. 1 key finding →
Participants: 426 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
We have established a valuable homogeneous single-center cohort which, by identifying groups of variables associated with high risk of MCI or dementia conversion, should help to clarify the early physiopathological mechanisms of AD and should provide avenues for prompt diagnosis and AD prevention. 2 key findings →
Design: cohort study Participants: 1,169 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
The trial was performed in 109 healthy subjects and 123 SDAT patients of whom 97 healthy subjects and 104 SDAT patients completed the study. 2 key findings →
Evidence: high
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The discovery cohort contained 3,671 individuals with a mean age of 68 years and consisted of 49% reported female. 5 key findings →
Participants: 3,671 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
LBD patients with AD copathology harbor greater neocortical SYN pathology. 1 key finding →
Participants: 36 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
In a prospective longitudinal study with death as the end point in 17 middle-aged patients with Down's syndrome, dementia was clinically diagnosed in 15 patients, by means of careful observations in daily circumstances. 2 key findings →
Design: longitudinal study Participants: 15 Evidence: moderate
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Both MSS and Activity sessions appear to be effective and appropriate therapies for people with dementia. 3 key findings →
Design: randomized controlled trial Evidence: high
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Virtual reality environments presented on tablets and smartphones have potential to aid the early diagnosis of conditions such as Alzheimer's dementia by quantifying impairments in navigation performance. 2 key findings →
Participants: 49 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
In sum, we present a diagnostic tool for MCI and AD trained using baseline scans and a follow-up diagnosis regardless of progression, which is multi-diagnostic, generalizable across independent data sources and acquisition protocols, and with transparently reported performance. 5 key findings →
Participants: 570 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
This study aims to systematically evaluate the efficacy of Pet robot intervention (PRI) for people with dementia. 4 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Full text may need a subscription
The results were validated in an independent sample of 610 patients with Parkinson's disease from the National Institute of Neurological Disorders and Stroke Parkinson's Disease Biomarker Program (PDBP). 2 key findings →
Design: longitudinal study Participants: 423 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
There are variations in the interventions, such as location and dosage. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
About 245 patients were included and postoperative delirium affected 12.2% (30/245) of the patients. 5 key findings →
Design: case-control study Participants: 245 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
There is a growing interest in using technology to provide meaningful activities for people living with dementia. 3 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Our review identified several measures of speech which may assist with diagnosis and classification, and consolidated the brain-behavior associations relating to speech in FTD, PPA, and progressive apraxia of speech. 1 key finding →
Design: meta-analysis Evidence: high
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Caregivers reported that digital mental health tools have an overall positive role in their health. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The proposed method offers a fully automated procedure, providing an opportunity to develop an inexpensive, broadly accessible, and easy-to-administer screening tool for MCI-to-AD progression prediction, facilitating development of remote assessment. 1 key finding →
Participants: 166 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Light Gradient-boosting Machine (LightGBM) achieved the highest performance in identifying agitation over an 8-day period with a sensitivity of 71.32% ± 7.38 and specificity of 75.28% ± 7.38. 5 key findings →
Design: longitudinal study Participants: 63 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Deriving disease subtypes from electronic health records (EHRs) can guide next-generation personalized medicine. 2 key findings →
Participants: 1,608,741 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Taking more anticholinergic medications is associated with greater risk of hospitalization for confusion or dementia. 3 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Hospitalised people with cognitive impairment experience significantly greater length of stay and when discharged to their usual residence are more likely to be readmitted to hospital within 28 days compared with those without cognitive impairment. 5 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Repeat HF hospitalizations remain a strong predictor of mortality for existing patients with HF. 3 key findings →
Participants: 51,286 Evidence: moderate
Full summary, score breakdown and related studies → Original source
A high proportion of residents with and without dementia are hospitalized shortly before death. 2 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Many VA nursing home residents have SMI. 1 key finding →
Design: cross-sectional Participants: 9,618 Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →