28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Normative developmental equations provide reliable descriptors of brain electrical activity in people 6 to 90 years old. 5 key findings →
Evidence: low
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The analysis of 14-3-3 protein in cerebrospinal fluid (CSF) was shown to be highly sensitive and specific for the diagnosis of Creutzfeldt-Jakob disease (CJD). 1 key finding →
Evidence: low
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In Alzheimer disease (AD), which is the most common cause of dementia, the underlying disease pathology most probably precedes the onset of cognitive symptoms by many years. 5 key findings →
Evidence: low
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Dementia remains under-diagnosed in the elderly population. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Braak and colleagues have proposed that, within the central nervous system, Parkinson's disease (PD) begins as a synucleinopathy in nondopaminergic structures of the lower brainstem or in the olfactory bulb. 1 key finding →
Evidence: low
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The objective of this study was to assess the prevalence and pattern of neuropsychological impairment in cohorts of human immunodeficiency virus (HIV)-infected individuals across pre- and post-HAART (highly active antiretroviral therapy) eras. 3 key findings →
Participants: 51 Evidence: low
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Although it has been suggested that variations in mean EEG frequency are greater in the former, the existence of meaningful differences remains controversial. 1 key finding →
Evidence: low
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This study utilized an initial dataset of 188,700 participant records from NACC. 5 key findings →
Participants: 16,309 Evidence: low
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This comprehensive review examines the integration of Quantitative Electroencephalography (qEEG) and Artificial Intelligence (AI) in the detection and diagnosis of Alzheimer's Disease (AD). 5 key findings →
Participants: 890 Evidence: low
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The proportion of false negatives from FDG-PET ranged from 11-55%. 5 key findings →
Design: longitudinal study Participants: 112 Evidence: moderate
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Of 394 participants, 35 % had preoperative CI on the MoCA, 15 % on the AD8, and 12 % on the Mini-Cog. 5 key findings →
Participants: 394 Evidence: low
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CDR-SB and MoCA scores showed strong inverse correlation (Spearman's ρ = -0.68; p < 0.001). 3 key findings →
Design: cross-sectional Participants: 23,717 Evidence: moderate
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NfL holds potential as a blood-based biomarker for symptomatic genetic FTD carriers, with moderate accuracy to distinguish PPD from mild forms including C9orf72 . 3 key findings →
Participants: 474 Evidence: low
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Symptoms of memory loss are caused by a range of cognitive abilities or a general cognitive decline, and not just memory. 4 key findings →
Evidence: low
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Olfactory dysfunction is among the earliest nonmotor features of Parkinson disease (PD). 1 key finding →
Evidence: low
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The Montreal Cognitive Assessment (MoCA) has been proved brief and sensitive to screen for mild cognitive impairment (MCI) and early dementia in some developed countries or areas. 2 key findings →
Evidence: low
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In a preliminary effort to improve the early diagnosis of dementia, we developed a regression-based method for estimating premorbid intelligence measured by the ability to read irregular words from the American version of the Nelson Adult Reading Test (AMNART). 1 key finding →
Design: cross-sectional Evidence: low
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This paper discusses the definition of apathy, reviews its differential diagnosis, and proposes a classification for the conditions that may produce it. 5 key findings →
Evidence: low
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The prevalence of severe dementia in the United States is about 1.3 million cases, of which at least 50 to 60% are of the Alzheimer type. 2 key findings →
Evidence: low
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Alzheimer's disease (AD) is the 3rd most costly disease and the leading cause of dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Altered consciousness has been regarded as a core feature of delirium; the fact that consciousness itself should be physiologically disrupted due to acute illness attests to its clinical urgency. 1 key finding →
Evidence: low
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Substantial heterogeneity in the design of included studies limits the ability to prognosticate for individual patients. 3 key findings →
Evidence: low
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The four IADL score could be incorporated into the screening procedure for dementia in elderly community dwellers. 1 key finding →
Evidence: low
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Female gender, older age, and lower levels of education were associated with poorer overall test scores. 3 key findings →
Design: cross-sectional Participants: 395 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Vision impairment is common among older adults and affects dementia screening assessments, which include visually presented items. 5 key findings →
Participants: 86 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →