27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
The findings of this study suggest that concurrent with new initiatives aimed at reducing hospitalizations, hospital transfers declined between 2011 and 2017 among nursing home residents with advanced illnesses without increased mortality rates. 2 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Residents dying with advanced dementia who received SNF care in the last 90 days of life had fewer aggressive treatments and lower odds of hospital death if they also received hospice care at any point during that time. 3 key findings →
Design: retrospective cohort Evidence: moderate
Full summary, score breakdown and related studies → Original source
There are specific risk factors associated with feeding tube placement in nursing home residents with severe cognitive impairment. 4 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Directives to forgo hospitalization for U.S. NH residents with advanced dementia are uncommon and are associated with the organizational features of the facilities caring for them and the intensity of end-of-life care practiced in the region, as well as individual resident characteristics. 5 key findings →
Design: cross-sectional Participants: 91,521 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Most NH residents who use statins at the time of progression to advanced dementia continue use in follow-up. 5 key findings →
Participants: 1,699 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The majority of hospitalizations of NH residents with advanced dementia were due to infections and thus were potentially avoidable, because infections are often treatable in the NH. 5 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Despite the growing number of persons with advanced dementia, and the need to improve their end-of-life care, few studies have addressed this important topic. 2 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The sources of stress for families of nursing home (NH) residents with advanced dementia have not been well described. 1 key finding →
Design: prospective cohort Evidence: moderate
Full summary, score breakdown and related studies → Original source
Our findings support need for greater ACP discussions between patients and proxies. 3 key findings →
Design: cross-sectional Participants: 14 Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia is a leading cause of death in the United States. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Nursing home residents dying with advanced dementia are not perceived as having a terminal condition, and most do not receive optimal palliative care. 1 key finding →
Participants: 1,609 Evidence: low
Full summary, score breakdown and related studies → Original source
Of 5406 nursing home residents with advanced dementia, 2911 (53.9%) received at least 1 medication with questionable benefit (range, 44.7% in the Mid-Atlantic census region to 65.0% in the West South Central census region). 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia is a leading cause of death in the USA. 3 key findings →
Participants: 8,686 Evidence: low
Full summary, score breakdown and related studies → Original source
Despite the difference in diagnostic indication for tube-feeding, the substitute decision-making process was seriously limited at both sites by poor implementation of the principle of substituted judgement, a need for broader advance directives, and improved transfer of knowledge between clinicians and decision-makers. 1 key finding →
Participants: 46 Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
Dual hospice/SNF access may result in fewer hospital deaths and higher quality of life for dying NH residents. 3 key findings →
Participants: 99,370 Evidence: low
Full summary, score breakdown and related studies → Original source
Medicare expenditures among nursing home residents with advanced dementia vary substantially. 4 key findings →
Participants: 323 Evidence: low
Full summary, score breakdown and related studies → Original source
More than 5 million Americans have dementia, a leading cause of death among persons older than 65 years in the United States. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Pneumonia, febrile episodes, and eating problems are frequent complications in patients with advanced dementia, and these complications are associated with high 6-month mortality rates. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Better communication, greater resident comfort, no tube feeding, and care in a specialized dementia unit are modifiable factors that may improve satisfaction with care in advanced dementia. 4 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
To understand family members' perspectives on person- and family-centered end-of-life care provided to nursing home (NH) residents with advanced dementia, we conducted a qualitative follow-up interview with 16 respondents who had participated in an earlier prospective study, Choices, Attitudes, and Strategies for Care of Advance Dementia at End of Life (CASCADE). 1 key finding →
Participants: 16 Evidence: low
Full summary, score breakdown and related studies → Original source
Persons with advanced dementia are frequently exposed to antimicrobials, especially during the 2 weeks before death. 2 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Based on the perceptions of bereaved family members, important opportunities exist to improve decision-making in feeding tube insertion. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Among nursing home residents with advanced cognitive impairment admitted to acute care hospitals, for-profit ownership, larger hospital size, and greater ICU use was associated with increased rates of feeding tube insertion, even after adjusting for patient-level characteristics. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Most feeding tubes are inserted in an acute care hospital. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The NH culture influences the approach to feeding in advanced cognitive impairment, whether by hand or placement of a feeding tube. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →