28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Proneness to experience psychological distress is a risk factor for AD, an effect independent of AD pathologic markers such as cortical plaques and tangles. 3 key findings →
Participants: 140 Evidence: low
Full summary, score breakdown and related studies → Original source
By incorporating sex, place of residence, age, and years of education as covariates, the TabCAT-BHA demonstrated greater accuracy in detecting cognitive impairment (AUC = 75.3%) compared to the MMSE (AUC = 66.4%) and RUDAS (AUC = 71.4%). 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
CR score was dose-dependently associated with disability/death (hazard ratio [HR] 0.96, 95% confidence interval [CI] 0.93-0.99). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Age and BMI were each associated with decreased brain volume. 3 key findings →
Participants: 114 Evidence: low
Full summary, score breakdown and related studies → Original source
Cognitive deficits and depression appear to be more common in aging former NFL players compared with healthy controls. 5 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Two-hundred and thirty-seven participants completed the 6-month post-intervention follow-up measures, 228 participants completed the 12-month measures, and 218 participants completed the 18-month measures. 5 key findings →
Participants: 272 Evidence: low
Full summary, score breakdown and related studies → Original source
Some studies have suggested that people with a high educational level have a lower risk of developing dementia compared to people with a low educational level. 4 key findings →
Participants: 1,022 Evidence: low
Full summary, score breakdown and related studies → Original source
Although modifiable risk factors may account for around 40 % of population variability in dementia risk, the effect of risk factor interrelationships on pathology-cognition relationships is poorly understood. 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Higher occupational attainment has previously been associated with increased Alzheimer's disease (AD) neuropathology when individuals are matched for cognitive function, indicating occupation could provide cognitive reserve. 3 key findings →
Participants: 323 Evidence: low
Full summary, score breakdown and related studies → Original source
Both Restriction (HR = 2.22, 95% CI [1.42, 3.47], P < .001) and Isolation (HR = 1.78, 95% CI [1.17, 2.70], P = 0.007) were associated with episodic memory and incident dementia, controlling for age, sex, and education. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Letter and category fluency tasks are used to assess semantic knowledge, retrieval ability, and executive functioning. 1 key finding →
Participants: 365 Evidence: low
Full summary, score breakdown and related studies → Original source
Higher SEP during childhood and greater educational attainment are both associated with cognitive function in adulthood, with mothers and fathers each contributing to their offspring's formative cognitive development and later life cognitive ability (albeit in different ways). 4 key findings →
Participants: 496 Evidence: low
Full summary, score breakdown and related studies → Original source
Early cognitive changes due to Alzheimer's disease (AD) include difficulties in semantic access and working memory. 2 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
AD was associated with lower PRS for premorbid cognitive performance, intelligence, and educational attainment. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Among individuals with mild cognitive impairment, no vision impairment (VI) and corrected VI were associated with a lower risk of dementia than uncorrected VI, particularly among those aged < 75 years. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Social activity was associated with global cognition, perceptual speed, perceptual orientation, and episodic memory over time. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
It is not known whether computerized cognitive assessments, like the CogState battery, are sensitive to preclinical cognitive changes or pathology in people at risk for Alzheimer's disease(AD). 4 key findings →
Participants: 71 Evidence: low
Full summary, score breakdown and related studies → Original source
The Galveston Orientation and Amnesia Test (GOAT) was developed to evaluate cognition serially during the subacute stage of recovery from closed head injury. 1 key finding →
Participants: 50 Evidence: low
Full summary, score breakdown and related studies → Original source
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and behaviours in response to changing environmental demands. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Greater social resources, as defined by social networks and social engagement, are associated with reduced cognitive decline in old age. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The National Adult Reading Test (NART) is widely used as a measure of premorbid IQ of the English-speaking patients with dementia. 1 key finding →
Participants: 50 Evidence: low
Full summary, score breakdown and related studies → Original source
These findings provide further evidence for a specific impairment in frontal-lobe functioning in the preclinical stages of AD in DS. 5 key findings →
Participants: 25 Evidence: low
Full summary, score breakdown and related studies → Original source
In this commentary I consider the issues raised in Schneider and Goldberg's review of composite cognitive and functional measures. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Cognition is a mental process that provides the ability to think, know, and learn. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
ObjectiveOlder individuals face a higher likelihood of developing dementia. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
10 of the 208 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →