Alzheimer disease will affect increasing numbers of people as baby boomers (persons born between 1946 and 1964) age. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
30,580 Alzheimer's and dementia studies in plain English, each scored out of 100.
Alzheimer disease will affect increasing numbers of people as baby boomers (persons born between 1946 and 1964) age. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, costs of care, and the overall impact on caregivers and society. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Under Medicare Part D, senior citizens choose prescription drug insurance offered by numerous private insurers. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
AADAPt participants had risk factors for developing dementia in future, such as hypertension and hyperlipidemia, but also reported protective factors such as high social engagement. 4 key findings →
Design: longitudinal study Participants: 177 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Subjective cognitive decline (SCD), the self-reported experience of worsening or more frequent memory loss or confusion, might be a symptom of early-stage dementia or future serious cognitive decline such as Alzheimer disease* or a related dementia (ADRD) (1). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The cost-effectiveness of ATTs is strongly influenced by the waning of the treatment effect. 1 key finding →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Biases in cognitive/functional screening tests may disproportionately exclude ethnoracial minorities in AD prevention trials. 1 key finding →
Participants: 6,669 Evidence: low
Full summary, score breakdown and related studies → Original source
These therapies require complex diagnostic workup and safety monitoring, raising significant budget impact concerns for healthcare payers. 2 key findings →
Participants: 11,568 Evidence: low
Full summary, score breakdown and related studies → Original source
Under calibrated simulation parameters, slowing of cognitive decline emerged as the most important attribute (relative importance 25.7%), followed by annual cost (17.6%), ARIA risk (15.4%), and travel to treatment centre (13.0%). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Simulation-based validation demonstrates the framework’s analytical capability. 5 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
In this trial, $5 and $25 noncontingent monetary incentives included in mailed recruitment letters did not produce a detectable improvement in response among ADRD caregiving dyads. 4 key findings →
Design: randomized controlled trial Participants: 103 Evidence: high
Full summary, score breakdown and related studies → Original source
STRUCTURED ABSTRACT INTRODUCTION This study examined the extent to which educational attainment, Alzheimer’s disease (AD) knowledge, and research attitudes are associated with willingness to participate in AD research, and whether AD knowledge and research attitudes mediate associations between educational attainment and willingness to participate. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Recruitment (88.0%) and protocol fidelity (100%) met or exceeded prespecified progression criteria, whereas retention and follow-up data availability were 59.1% (13/22), slightly below the predefined 60% criterion. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Our findings reveal marked geographic variation in dementia risk factors, highlighting the need for region-specific prevention strategies. 4 key findings →
Participants: 40,000 Evidence: low
Full summary, score breakdown and related studies → Original source
Cognitive staging and everyday function are not interchangeable. 1 key finding →
Design: retrospective cohort Participants: 202,508 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The increasing prevalence of neurodegenerative diseases (NDs), especially Alzheimer's and Parkinson's, is a major public health concern in the Gulf countries (GCs) due to the rapid increase in life expectancy and population aging. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Higher UGS coverage was associated with a lower risk of incident AD among older adults in urban South Korea. 4 key findings →
Design: cohort study Participants: 95,822 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Among 1,288,359 women, 20,070 with AUD were matched to 100,339 controls. 3 key findings →
Design: prospective cohort Evidence: moderate
Full summary, score breakdown and related studies → Original source
Internet use for health information was significantly associated with Alzheimer’s disease diagnosis. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The prognostic significance of psychosis in dementia differs by symptom profile. 4 key findings →
Participants: 21,108 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The multifactorial interventions implemented in community settings showed no effect on dementia onset or health outcomes. 5 key findings →
Participants: 256 Evidence: low
Full summary, score breakdown and related studies → Original source
Among adults with ADRD, high SDM was associated with greater ACP prevalence in unadjusted analyses, although the fully adjusted association was not statistically significant. 5 key findings →
Participants: 3,635 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Recorded PD-related mortality was lower among Black than White adults, whereas AD-related mortality showed no statistically significant racial difference. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
People with Down syndrome have higher age-specific mortality rates compared to the general population as well as peers with other intellectual and developmental disabilities. 2 key findings →
Design: case-control study Participants: 137,293 Evidence: moderate
Full summary, score breakdown and related studies → Original source
We recommend using a broad (ADRD) algorithm without CMS or medication data, particularly for epidemiological studies or a strict AD algorithm including CMS and medication cases for genetic discovery of late-onset AD associations in VA EMR, and a strict AD algorithm without CMS data for applications focused solely on AD and sensitive to misspecification. 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
8 of the 266 studies in this tag that have a study page, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 30,580 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,580 records, built mostly from automated pulls of Europe PMC (64.7% of the library) and OpenAlex (16.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,037 records (3.4% of the library) are not peer-reviewed — 964 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →
Newest studies, as a dated timeline → Atom feed Where this research is being discussed: events