27,780 Alzheimer's and dementia studies in plain English, each scored out of 100.
Mushrooms have been consumed since earliest history; ancient Greeks believed that mushrooms provided strength for warriors in battle, and the Romans perceived them as the "Food of the Gods." 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Antioxidants are substances that may protect cells from the damage caused by unstable molecules such as free radicals. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) enforce an overwhelming social and economic burden on society. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The use of complementary medicines, such as plant extracts, in dementia therapy varies according to the different cultural traditions. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Baum, Larry PhD; Lam, Christopher Wai Kei PhD; Cheung, Stanley Kwok-Kuen MSc; Kwok, Timothy MD; Lui, Victor MRCPsych; Tsoh, Joshua MRCPsych; Lam, Linda MD, MRCPsych; Leung, Vivian FHKCPsy; Hui, Elsie FRCP; Ng, Chelsia HBSc; Woo, Jean MD; Chiu, Helen Fung Kum FRCPsych; Goggins, William B. ScD; Zee, Benny Chung-Ying PhD; Cheng, King Fai MD; Fong, Carmen Yuet Shim RN; Wong, Adrian BSc; Mok, Hazel BSc; Chow, Moses Sing Sum PharmD; Ho, Ping Chuen PhD; Ip, Siu Po PhD; Ho, Chung Shun PhD; Yu, Xiong Wen PhD; Lai, Caroline Yau Lin MMedSc; Chan, Ming-Houng FHKCPhys; Szeto, Samuel FRCP; Chan, Iris Hiu Shuen PhD; Mok, Vincent MD Author Information 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Cognitive dysfunction is a major health problem in the 21st century, and many neuropsychiatric disorders and neurodegenerative disorders, such as schizophrenia, depression, Alzheimer's Disease dementia, cerebrovascular impairment, seizure disorders, head injury and Parkinsonism, can be severly functionally debilitating in nature. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Black pepper is an autoicous and decorous vine cultivated and harvested in tropical regions of Sri Lanka and India. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
For example, the early advances in floral genetics were primarily the result of the ease of screening for mutations impacting flavonoid-derived flower colors, and the first demonstration of epigenetic gene silencing in plants was likewise associated with flavonoid biosynthesis (Jorgensen, 1995). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer’s disease (AD) is a neurodegenerative disease associated with amyloid-β (Aβ) deposition, leading to neurotoxicity (oxidative stress and neuroinflammation) and gut microbiota imbalance. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Several epidemiological studies indicate that moderate consumption of wine is associated with a lower incidence of Alzheimer's disease. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Metformin was originally derived from a botanical ancestry and became the most prescribed, first-line therapy for Type 2 diabetes in most countries. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Hesperetin is a bioactive flavonoid in the body, produced from hesperidin. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Docosahexaenoic acid (DHA), a polyunsaturated fatty acid (PUFA) enriched in phospholipids in the brain and retina, is known to play multi-functional roles in brain health and diseases. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
As a result, it has been reported that changes in endocannabinoid levels may be related to neurological diseases such as Parkinson's disease, Huntington's disease, Alzheimer's disease and multiple sclerosis, as well as anorexia and irritable bowel syndrome. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The frequently studied polysaccharide, chitosan oligosaccharide/chitooligosaccharide (COS) is the major degradation product of chitosan/chitin via chemical hydrolysis or enzymatic degradation involving deacetylation and depolymerization processes. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease associated with memory and cognition impairment ultimately leading to death. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Tea, leaf, or bud from the plant Camellia sinensis, make up some of the beverages popularly consumed in different parts of the world as green tea, oolong tea, or black tea. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Curcumin (Cur), a natural compound from Curcuma longa Linn, has various of pharmacological activities such as anti-cancer, anti-inflammatory, anti-oxidant, anti-Alzheimer, anti-microbial and more. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Aloe-emodin is a naturally anthraquinone derivative and an active ingredient of Chinese herbs, such as Cassia occidentalis, Rheum palmatum L., Aloe vera, and Polygonum multiflorum Thunb. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Cerium oxide nanoparticles (CeONPs) have attracted much attention because they possess multi-enzyme mimetic properties and have been used in bioanalysis, biomedicine, drug delivery, bioscaffold and so on. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Curcumin is a natural polyphenol with evidence of antioxidant, anti-inflammatory and neuroprotective properties. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The results of the present study confirm in vivo anti-inflammatory actions of CBD, emphasizing the importance of this compound as a novel promising pharmacological tool capable of attenuating Abeta evoked neuroinflammatory responses. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
A growing body of epidemiological evidence suggests that fruit and vegetable juices containing various phenolic compounds can reduce the risk of Alzheimer's disease (AD). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The review is focused on the currently major aspect of 4-hydroxynonenal (HNE) research--studies that combine biological activities of the aldehyde together with the methods of its identification in cells and tissues. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Omega-3 [(n-3)] fatty acids have been linked to healthy aging throughout life. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
8 of the 119 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,780 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,780 records, built mostly from automated pulls of Europe PMC (61.1% of the library) and OpenAlex (18.3%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →