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Research

30,980 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 276–300 of 653 studies of type cross-sectional study · free to read (page 12 of 27) · 30,980 in the whole library · How the 0–100 score works

Download bibliography of the first 500 of these studies, in this order: BibTeX (.bib) · RIS (.ris)

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 16,452 studies have no institution on record and are not counted here.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

White matter hyperintensity severity modifies gut metabolite association with cognitive outcomes

✓ Peer-reviewed alzhub usefulness score 55 out of 100. The Journal of Prevention of Alzheimer s Disease 2025-02-11

Of 104 metabolites studied, glycodeoxycholic acid (GDCA) surpassed the false discovery rate and was associated the Alzheimer's Disease Assessment Scale-Cognitive Subscale version 13 (ADAS-Cog13) score (β = 0.12, 95 % CI = 0.05-0.20, p = 0.001) and cognitive impairment determined by mini-mental status exam (MMSE) (OR = 2.11, 95 % CI = 1.41-3.15, p < 0.001). 4 key findings →

Design: cross-sectional Participants: 578 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Diagnostic Utility of Cerebrospinal Fluid Biomarkers in Patients with Rapidly Progressive Dementia

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Annals of neurology 2023-11-10

Selected CSF biomarkers at presentation were associated with etiologic diagnoses and treatment responsiveness in patients with heterogeneous causes of RPD. 3 key findings →

Design: cross-sectional Participants: 44 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Can physicians conceive of performing euthanasia in case of psychiatric disease, dementia or being tired of living?

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of medical ethics 2015-02-18

This study shows that a minority of Dutch physicians find it conceivable that they would grant a request for EAS from a patient with psychiatric disease, dementia or a patient who is tired of living. 2 key findings →

Design: cross-sectional Participants: 1,456 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Chronic disease prevalence and care among the elderly in urban and rural Beijing, China - a 10/66 Dementia Research Group cross-sectional survey

✓ Peer-reviewed alzhub usefulness score 54 out of 100. BMC public health 2009-10-21

Apparent better health in Daxing might be explained by under-diagnosis, under-reporting or selective mortality. 3 key findings →

Design: cross-sectional Participants: 1,002 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2010-09-01

These plasma ceramides may be early indicators of AD progression. 3 key findings →

Design: cross-sectional Participants: 25 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Structural covariance of the default network in healthy and pathological aging

✓ Peer-reviewed alzhub usefulness score 54 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2013-09-01

Significant progress has been made uncovering functional brain networks, yet little is known about the corresponding structural covariance networks. 3 key findings →

Design: cross-sectional Participants: 414 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Alzheimer disease pathology and the cerebrospinal fluid proteome

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Alzheimer's research & therapy 2018-07-18

Altered proteome profiles have been reported in both postmortem brain tissues and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with AD pathology, amyloid pathology, and tau-related neurodegeneration have not yet been fully explored. 4 key findings →

Design: cross-sectional Participants: 48 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

State Department of Motor Vehicles Reporting Mandates of Dementia Diagnoses and Dementia Underdiagnosis

✓ Peer-reviewed alzhub usefulness score 54 out of 100. JAMA Network Open 2024-04-25

Four states have clinician reporting mandates, 14 have mandates requiring drivers to self-report dementia diagnoses, and 32 states and the District of Columbia do not have explicit requirements. 5 key findings →

Design: cross-sectional Participants: 35 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Inequities in Filled Overactive Bladder Medication Prescriptions in the US

✓ Peer-reviewed alzhub usefulness score 54 out of 100. JAMA Network Open 2023-05-24

An estimated 2 971 449 individuals (mean age, 66.4 years; 95% CI, 64.8-68.2 years) filled prescriptions for OAB medications in 2019; 2 185 214 (73.5%; 95% CI, 62.6%-84.5%) identified as female, 2 326 901 (78.3%; 95% CI, 66.3%-90.3%) self-identified as non-Hispanic White, 260 685 (8.8%; 95% CI, 5.0%-12.5%) identified as non-Hispanic Black, 167 210 (5.6%; 95% CI, 3.1%-8.2%) identified as Hispanic, 158 507 (5.3%; 95% CI, 2.3%-8.4%) identified as non-Hispanic other race, and 58 147 (2.0%; 95% CI, 0.3%-3.6%) identified as non-Hispanic Asian. 5 key findings →

Design: cross-sectional Participants: 449 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Understanding Medicare: Hearing Loss and Health Literacy

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of the American Geriatrics Society 2020-08-03

Medicare beneficiaries with a little or a lot of trouble hearing had 18% (95% confidence interval [CI] odds ratio [OR] = 1.10-1.27) and 25% (95% CI OR = 1.07-1.47) increased odds of reporting greater difficulty with understanding Medicare, respectively, compared with those with no hearing trouble. 3 key findings →

Design: cross-sectional Participants: 10,510 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Variability in Clinical Performance of the FDA-Cleared Lumipulse P-Tau217/β-Amyloid 1-42 Plasma Ratio

✓ Peer-reviewed alzhub usefulness score 54 out of 100. JAMA Neurology 2026-06-01

This cross-sectional study evaluates the performance of the US Food and Drug Administration–cleared phosphorylated tau 217 (p-tau217) to β-amyloid 42 ratio cut points used to detect amyloid pathology associated with Alzheimer disease. 1 key finding →

Design: cross-sectional Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Pulling Back the Curtain on Hospital Dementia Detection: Validation of the Informant‐Based Clinical Dementia Rating

✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of the American Geriatrics Society 2025-05-02

Of 65 participants (mean age = 79.4 years; women = 54%), 34% had dementia and 32% had CIND. 5 key findings →

Design: cross-sectional Participants: 65 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Economic Burden of Alzheimer Disease and Related Dementias by Race and Ethnicity, 2020 to 2060

✓ Peer-reviewed alzhub usefulness score 54 out of 100. JAMA Network Open 2025-06-05

Of 31 028 older adults in MEPS, 5184 (10%) were African American; 146 (<1%) American Indian or Alaska Native; 1043 (3%) Asian (Indian, Chinese, or Filipino); 5346 (10%) Latino; 690 (2%) Other Asian, Native Hawaiian, and Pacific Islander; and 18 617 (75%) were White. 5 key findings →

Design: cross-sectional Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Annals of neurology 2025-12-25

In this real-world dataset, we identified effects of multimorbidities on plasma biomarkers, especially kidney function. 2 key findings →

Design: cross-sectional Participants: 617 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Frontiers in neurology 2019-04-24

The extent to which Alzheimer neuropathology, particularly the accumulation of misfolded beta-amyloid, contributes to cognitive decline and dementia in Parkinson's disease (PD) is unresolved. 1 key finding →

Design: cross-sectional Participants: 23 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

TauIQ: A Canonical Image Based Algorithm to Quantify Tau PET Scans

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2021-01-30

Tau IQ successfully calculated global tau load (Tau L ) in all 791 scans analyzed (range, -3.5% to 185.2%; mean ± SD, 23% ± 20.5%) with a nonzero additional local tau component being required in 31% of all scans (cognitively normal [CN], 22%; mild cognitive impairment [MCI], 35%; dementia, 72%). 5 key findings →

Design: cross-sectional Participants: 615 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Serum NfL in Alzheimer Dementia: Results of the Prospective Dementia Registry Austria

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Medicina (Kaunas, Lithuania) 2022-03-16

Higher sNfL concentrations were associated with worse performance in cognitive tests at baseline, including CERAD (B = −10.084, SE = 2.999, p < 0.001) and MMSE (B = −3.014, SE = 1.293, p = 0.021). 3 key findings →

Design: cross-sectional Participants: 237 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Patient and caregiver characteristics associated with depression in caregivers of patients with dementia

✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of general internal medicine 2003-12-01

The goal of this study was to determine the patient and caregiver characteristics associated with depression among caregivers of patients with dementia. 4 key findings →

Design: cross-sectional Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

↑ Change the filters

Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 30,980 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,980 records, built mostly from automated pulls of Europe PMC (65.2% of the library) and OpenAlex (16.4%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,040 records (3.4% of the library) are not peer-reviewed — 965 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed    Where this research is being discussed: events