alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Research

30,980 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 101–125 of 369 studies · free to read (page 5 of 15) · 30,980 in the whole library · How the 0–100 score works

Download bibliography of these 369 studies, in this order: BibTeX (.bib) · RIS (.ris)

Showing 369 studies tagged palliative — clear

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 16,452 studies have no institution on record and are not counted here.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Machine learning-based prediction of short- and long-term mortality for shared decision-making in older hip fracture patients: the Dutch Hip Fracture Audit algorithms in 74,396 cases

✓ Peer-reviewed alzhub usefulness score 59 out of 100. Acta Orthopaedica 2025-07-07

74,396 patients (median age 84, IQR 78-89; 68% female) were analyzed. 5 key findings →

Design: cohort study Participants: 74,396 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Implications of the COVID-19 Pandemic on Adult Day Services and the Families They Serve

✓ Peer-reviewed alzhub usefulness score 59 out of 100. American journal of Alzheimer's disease and other dementias 2021-10-15

The COVID-19 pandemic forced adult day services (ADS) to close and abruptly end in-person services to clients. 5 key findings →

Design: randomized controlled trial Participants: 19 Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics

✓ Peer-reviewed alzhub usefulness score 58 out of 100. Neuroepidemiology 2008-02-07

Strengths of the study are that the subjects were randomly selected from a defined population, the majority of the subjects were examined in person, and MCI was defined using published criteria. 1 key finding →

Participants: 2,719 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Total and cause-specific mortality in the cardiovascular health study

✓ Peer-reviewed alzhub usefulness score 58 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2009-09-01

In these older adults, associations of risk factors with a given cause of death were related to specific deficits in that same organ system. 2 key findings →

Design: cohort study Participants: 5,888 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Comparing post-acute rehabilitation use, length of stay, and outcomes experienced by Medicare fee-for-service and Medicare Advantage beneficiaries with hip fracture in the United States: A secondary analysis of administrative data

✓ Peer-reviewed alzhub usefulness score 58 out of 100. PLoS Medicine 2018-06-26

This was a retrospective cohort study to examine differences in health service utilization and outcomes between FFS and MA patients in SNFs following hip fracture hospitalization during the period January 1, 2011, to June 30, 2015, and followed up until December 31, 2015. 5 key findings →

Design: cohort study Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Exercise therapy for the treatment of delirium in the intensive care unit

✓ Peer-reviewed alzhub usefulness score 58 out of 100. Cochrane Database of Systematic Reviews 2025-08-12

Outcomes of interest were duration of delirium, health-related quality of life, delirium severity, cognitive function, mortality in the ICU, ICU length of stay, hospital length of stay and adverse events. 5 key findings →

Design: meta-analysis Participants: 491 Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

Physical activity and functional limitations in older adults: a systematic review related to Canada's Physical Activity Guidelines

✓ Peer-reviewed alzhub usefulness score 57 out of 100. The international journal of behavioral nutrition and physical activity 2010-05-11

Sixty-six studies met inclusion criteria for the relationship between physical activity and functional independence, and 34 were included with a cognitive function outcome. 4 key findings →

Design: cohort study Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Postoperative delirium: a 76-year-old woman with delirium following surgery

✓ Peer-reviewed alzhub usefulness score 57 out of 100. JAMA 2012-07-01

Delirium (acute confusion) complicates 15% to 50% of major operations in older adults and is associated with other major postoperative complications, prolonged length of stay, poor functional recovery, institutionalization, dementia, and death. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Long-term health outcomes in a British cohort of breast, colorectal and prostate cancer survivors: a database study

✓ Peer-reviewed alzhub usefulness score 57 out of 100. British journal of cancer 2011-11-01

The study confirms the occurrence of increased incidence of chronic illnesses in long-term cancer survivors attributable to underlying lifestyle and/or cancer treatments. 2 key findings →

Participants: 26,213 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Caregiving burden, stress, and health effects among family caregivers of adult cancer patients

✓ Peer-reviewed alzhub usefulness score 57 out of 100. JAMA 2012-01-01

Unlike professional caregivers such as physicians and nurses, informal caregivers, typically family members or friends, provide care to individuals with a variety of conditions including advanced age, dementia, and cancer. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: Beyond mortality from cardiopulmonary disease and lung cancer

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Environment international 2022-04-12

Long-term exposure to PM 2.5 , NO 2 , and/or BC in Denmark were associated with mortality beyond cardiorespiratory diseases, including diabetes, dementia, psychiatric disorders, asthma, and ALRI. 5 key findings →

Participants: 803,881 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Machine Learning Algorithm Using Electronic Chart-Derived Data to Predict Delirium After Elderly Hip Fracture Surgeries: A Retrospective Case-Control Study

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Frontiers in surgery 2021-07-13

About 245 patients were included and postoperative delirium affected 12.2% (30/245) of the patients. 5 key findings →

Design: case-control study Participants: 245 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

The evolution of serious health-related suffering from 1990 to 2021: an update to The Lancet Commission on global access to palliative care and pain relief

✓ Peer-reviewed alzhub usefulness score 57 out of 100. The Lancet Global Health 2025-02-26

The SHS global burden increased by 74% between 1990 and 2021 to almost 73·5 million individuals, with population growth accounting for only half of that increase. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Investigating three ways of measuring the intrinsic capacity domain of vitality: nutritional status, handgrip strength and ageing biomarkers

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Age and ageing 2023-07-01

Vitality was associated with disability primarily through the mediation of other IC domains. 2 key findings →

Design: longitudinal study Participants: 1,389 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Race Differences in Characteristics and Experiences of Black and White Caregivers of Older Americans

✓ Peer-reviewed alzhub usefulness score 56 out of 100. The Gerontologist 2020-09-01

Relative to white caregivers, blacks more often provided in excess of 40 hr of care per week (54.3% vs 38.6%) and more often cared for an older adult with dementia (27.1% vs 20.7%) who was living below the federal poverty line (31.7% vs 11.9%) or was Medicaid-eligible (42.2% vs 11.8%). 1 key finding →

Participants: 992 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Dementia, Alzheimer's Disease, and Mortality after Hemodialysis Initiation

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Clinical journal of the American Society of Nephrology : CJASN 2018-08-09

Older patients on hemodialysis are at substantial risk of diagnosis with dementia and Alzheimer's disease, and carrying these diagnoses is associated with a twofold higher mortality. 4 key findings →

Participants: 356,668 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Back to the future – feasibility of recruitment and retention to patient education and telephone follow-up after hip fracture: a pilot randomized controlled trial

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Patient Preference and Adherence 2015-09-01

Our pilot study results indicate that it is feasible to recruit, retain, and provide follow-up telephone coaching to older adults after hip fracture. 5 key findings →

Design: randomized controlled trial Participants: 30 Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

Variation in use of antipsychotic medications in nursing homes in the United States: A systematic review

✓ Peer-reviewed alzhub usefulness score 55 out of 100. BMC geriatrics 2017-01-26

Variation in use of APMs in U.S. nursing homes based upon facility characteristics exemplifies the need for a more systematic protocol guiding the use of these medications, along with heightened regulatory policies and enforcement. 2 key findings →

Design: meta-analysis Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

Machine-learning-based COVID-19 mortality prediction model and identification of patients at low and high risk of dying

✓ Peer-reviewed alzhub usefulness score 55 out of 100. Critical care (London, England) 2021-09-08

An accurate COVID-19 mortality prediction model among hospitalized patients based on the clinical features and comorbidities may play a beneficial role in the clinical setting to better management of patients with COVID-19. 3 key findings →

Participants: 250 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Patient-related risk factors for postoperative mortality and periprosthetic joint infection in medicare patients undergoing TKA

✓ Peer-reviewed alzhub usefulness score 55 out of 100. Clinical orthopaedics and related research 2012-01-01

We believe this information important when counseling elderly patients regarding the risks of mortality and PJI after TKA and risk-adjusting publicly reported TKA patient outcomes. 2 key findings →

Participants: 83,011 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

↑ Change the filters

Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 30,980 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,980 records, built mostly from automated pulls of Europe PMC (65.2% of the library) and OpenAlex (16.4%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,042 records (3.4% of the library) are not peer-reviewed — 967 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed    Where this research is being discussed: events