Mean scores of emotional distress were significantly higher in carers at each time point than in controls (all p<0.0003). 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Mean scores of emotional distress were significantly higher in carers at each time point than in controls (all p<0.0003). 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease (AD), the leading cause of dementia, is a growing health issue with very limited treatment options. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Microcystin-leucine-arginine (MC-LR) is a toxin secreted by freshwater cyanobacteria that is considered a potential environmental risk factor for Alzheimer's disease (AD). 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Given the unknown therapeutic value of targeting Alzheimer's disease pathology and the discovery of robust risk factors for dementia, non-pharmacological risk reduction (RR) is increasingly offered as an alternative to targeting Alzheimer's disease pathology. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Since environmental, socioeconomic, and individual risk factors contribute to dementia, we proposed a Comprehensive, Customized, Cost-effective APProach (the CCC-APP) implemented in actionable units with the focus on promoting brain health (eumentia). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Cognitive reserve is originally an epidemiological concept that encompasses individual abilities to cope with changes. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease is a progressive brain disease that is becoming a major health problem in today's world due to the aging population. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
several dietary components have been positively associated with AD prevention, including intake of complex carbohydrates, fiber, omega-3, plant-based proteins, vitamins (folates, choline, vitamin D, C, B6 and B9), zinc, some bioactive compounds such as flavonols and probiotics. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Stroke has three main subtypes - ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Individuals with unipolar depressive disorder (UDD) are having an increased risk of death and development of dementia in later life. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia is a growing public health concern, with an estimated prevalence of 57 million adults worldwide. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Mediterranean diet (MD) accurately lowers AD (Alzheimer's Disease) risk to 53% and 35% for people who follow it moderately. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
During Alzheimer's (AD), tau protein suffers from abnormal post-translational modifications, including cleaving by caspase-3. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
P021 treatment during early development prevented cognitive impairment and increased expressions of pCREB and BDNF that activated downstream various signaling cascades such as PLC/PKC, MEK/ERK and PI3K/Akt, and ameliorated synaptic protein deficit in 4-month-old 3xTg-AD mice. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
PLCG2 expression is restricted primarily to microglia and granule cells of the dentate gyrus. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
> 0.95) and is present in all African ancestry tested. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dementia, is a critical global public health challenge with no effective pharmacological treatments. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
LPA identified four intrinsic profiles: Profile 1 had low motivation; Profile 2 had high motivation and self-efficacy, but poor dementia knowledge; Profile 3 had moderate motivation; and Profile 4 had low motivation and high apathy. 5 key findings →
Participants: 347 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Metabolic syndrome (MetS) is characterized by central obesity, insulin resistance, hypertension, dyslipidemia, and chronic inflammation, significantly increasing the risk of cardiovascular disease and type 2 diabetes. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Gastric cancer, a prevalent malignant tumor worldwide, poses a significant challenge to global health. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Over the past decade, Latin America and the Caribbean (LAC) have made progress in implementing the Sendai Framework for Disaster Risk Reduction 2015–2030 (SFDRR). 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
With the aging of the population, the number of persons with dementia is expected to increase worldwide, making the establishment of preventive strategies for dementia an urgent issue. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Age-related macular degeneration (AMD) is a multifactorial disorder influenced by genetic, lifestyle, nutritional, and systemic health factors that contribute to increased oxidative stress and chronic inflammation in the retina. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
IFAD activities led to substantial progress in dementia care services, with memory clinics, residential care facilities and daycare centres mapped, revealing regional disparities in service provision. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Among 160 centenarians, 63.7% did not meet the PCFP criteria and were classified as having dementia. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
10 of the 859 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →