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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 2,426–2,450 of 7,816 matching trials · page 98 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
NCT04408755
AVP-786; Placebo
Runs in: Bulgaria; Denmark; Estonia; Germany; Greece; Poland; Port... · 95 sites 		PHASE3
other		 TERMINATED 184 Otsuka Pharmaceutical Development & Commercialization, Inc.
INDUSTRY		 2025-05-30
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
NCT04464564
AVP-786; Placebo
Runs in: Belgium; Canada; Chile; Colombia; Croatia; Hungary; Irela... · 106 sites 		PHASE3
other		 TERMINATED 241 Otsuka Pharmaceutical Development & Commercialization, Inc.
INDUSTRY		 2025-05-30
Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease
NCT05968703
Combined STN+NBM DBS
Runs in: United States · 1 site 		NA
other		 RECRUITING 10 Helen M. Bronte-Stewart
OTHER		 2025-05-30
Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis
NCT06339190
Venepuncture
Runs in: Australia · 2 sites 		NA
other		 RECRUITING 1,000 Monash University
OTHER		 2025-05-30
Investigating the Efficacy of an Augmented Virtual Reality Driving Simulator on Institutionalized Dementia Patients
NCT06419257
VRDS
Runs in: Canada · 1 site 		NA
other		 RECRUITING 20 University of Manitoba
OTHER		 2025-05-30
A Socio-Technological Intervention in Community-Based Healthcare for Individuals With Mild Cognitive Impairment (DHEAL-COM-MCI)
NCT06984367
socio-technical intervention; Usual care
Runs in: Italy · 1 site 		NA
other		 RECRUITING 60 Istituto Nazionale di Ricovero e Cura per Anziani
OTHER		 2025-05-30
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
NCT01793168
Runs in: Australia; United States · 2 sites 		NA
other		 RECRUITING 20,000 Sanford Health
OTHER		 2025-05-29
Effects of Square-stepping Exercise on Frailty and Cognitive Function in Elderly With Frailty and MCI
NCT04463797
Square-stepping exercise; Stretching and strengthening
Runs in: Taiwan · 1 site 		NA
other		 COMPLETED 31 National Yang Ming Chiao Tung University
OTHER		 2025-05-29
Influence of Square-stepping Exercise on Brain Activation, Cognitive Function and Physical Performance in Frail Elders With MCI
NCT05173363
Runs in: Taiwan · 1 site 		NA
other		 COMPLETED 25 National Yang Ming Chiao Tung University
OTHER		 2025-05-29
Promoting In-Home Activities at a Memory & Aging Clinic
NCT05771064
Gentle Moves
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 28 University of Illinois at Chicago
OTHER		 2025-05-29
A Study Assessing the Safety and Tolerability of LY03020 in Chinese Healthy Subjects
NCT06556966
LY03020; Placebo
Runs in: China · 1 site 		PHASE1
other		 COMPLETED 66 Luye Pharma Group Ltd.
INDUSTRY		 2025-05-29
German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)
NCT06711952
Subjective Cognitive Decline-Questionnaire (SCD-Q); Cognitive Failu...
Runs in: Germany · 1 site 		NA
other		 RECRUITING 300 Ludwig-Maximilians - University of Munich
OTHER		 2025-05-29
Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention
NCT06986096
Aerobic-strength training and nutritional counseling; Cognitive tra...
Runs in: Slovakia · 1 site 		NA
other		 RECRUITING 40 Slovak Academy of Sciences
OTHER_GOV		 2025-05-29
Effect of Tetrabenazine on Stroop Interference in HD
NCT01834911
Tetrabenazine withdrawal
Runs in: United States · 1 site 		PHASE4
other		 COMPLETED 2 New York Medical College
OTHER		 2025-05-28
Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease
NCT03330470
exercise; carnosine supplementation; stretching; supplementation wi...
Runs in: Slovakia; Taiwan · 3 sites 		NA
other		 COMPLETED 26 Slovak Academy of Sciences
OTHER_GOV		 2025-05-28
Personalized Prevention of Depression in Primary Care
NCT03990792
e-predictD intervention; Brief psychoeducational intervention
Runs in: Spain · 6 sites 		NA
other		 COMPLETED 663 The Mediterranean Institute for the Advance of Biotechnology and Health Research
OTHER		 2025-05-28
Swiss Postpartum Hypertension Cohort
NCT04690660
Data collection for parameters of organ damage (cardiac and renal b...
Runs in: Switzerland · 1 site 		NA
other		 RECRUITING 480 University Hospital, Basel, Switzerland
OTHER		 2025-05-28
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
NCT06644573
PROSOMNIA Sleep Therapy™ (PSTx); Anesthesia-Induced Sleep Therapy; ...
Runs in: United States · 1 site 		PHASE1
other		 NOT_YET_RECRUITING 100 Nyree Penn
INDUSTRY		 2025-05-28
Effectiveness of a 3-month Individual Reminiscence Therapy Program in Older Adults With Alzheimer's Disease
NCT06812442
Reminiscence therapy
Runs in: Portugal · 4 sites 		NA
other		 COMPLETED 40 Rsocialform - Geriatria, Lda
OTHER		 2025-05-28
Deep Cervical Lymphaticovenous Anastomosis Surgery for Moderate-to-Advanced Dementia Patients
NCT06978946
Deep Cervical Lymphaticovenous Anastomosis(DLVA)
Runs in: China · 1 site 		NA
other		 NOT_YET_RECRUITING 85 RenJi Hospital
OTHER		 2025-05-28
Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury
NCT06993194
Haloperidol; Dexmedetomidine 		NA
other		 NOT_YET_RECRUITING 40 Benha University
OTHER		 2025-05-28
HOme-based Brain Monitoring With a GARment-EEG to Study Cognitive Decline in the Aging Population
NCT06993207
Home Lab
Runs in: Spain · 1 site 		NA
other		 RECRUITING 500 Bitbrain
INDUSTRY		 2025-05-28
Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease
NCT04994483
Simufilam; Placebo
Runs in: Australia; Canada; United States · 88 sites 		PHASE3
other		 COMPLETED 804 Cassava Sciences, Inc.
INDUSTRY		 2025-05-25
Clinical Trial of AGB101 for Mild Cognitive Impairment
NCT05986721
AGB101; Placebo
Runs in: United States · 1 site 		PHASE2
other		 WITHDRAWN 0 AgeneBio
INDUSTRY		 2025-05-25
Ultrasonic Neuromodulation for Treatment of Cognitive Impairment
NCT06135051
Diadem prototype
Runs in: United States · 1 site 		PHASE1|PHASE2
other		 TERMINATED 1 University of Utah
OTHER		 2025-05-25

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →