Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 2,326–2,350 of 7,816 matching trials · page 94 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Music Interventions for Dementia and Depression in Elderly Care
NCT03496675
Group Music Therapy; Recreational Choir Singing; Standard care
Runs in: Australia; Germany; Netherlands; Norway; Turkey (Türkiye)... · 6 sites
NA
other
COMPLETED 1,021 NORCE Norwegian Research Centre AS
OTHER
2025-07-09
Intergenerational Behavioral Intervention to Enhance Physical Activity in Older Adults at Risk for Alzheimer's Disease
NCT06038643
Motivational behavioural intervention and daily activities monitori...
Runs in: Canada · 1 site
NA
other
COMPLETED 76 Douglas Mental Health University Institute
OTHER
2025-07-09
White Matter Hyperintensities in Amnestic Mild Cognitive Impairment or Alzheimer's Disease
NCT06179680
Magnetic Resonance Imaging
Runs in: Italy · 1 site
NA
other
RECRUITING 142 IRCCS Policlinico S. Donato
OTHER
2025-07-09
Sleep Stimulation to Enhance Waste Clearance in the Brain
NCT07051239
Closed-loop acoustic stimulation
Runs in: Belgium · 1 site
NA
other
NOT_YET_RECRUITING 105 Erasme University Hospital
OTHER
2025-07-09
Safety, Pharmacokinetics and Pharmacodynamics of Velusetrag in Healthy Elderly Subjects
NCT01467726
Velusetrag; Velusetrag; Placebo
Runs in: United States · 1 site
PHASE1
other
COMPLETED 40 Alfasigma S.p.A.
INDUSTRY
2025-07-08
Neurobic Exercise Program on Cognitive Abilities
NCT06601751
Neurobic Exercise Program; Traditional Brain Exercise
Runs in: Pakistan · 1 site
NA
other
COMPLETED 44 Riphah International University
OTHER
2025-07-08
hUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases
NCT06607900
hUC-MSC-sEV-001 nasal drops
Runs in: China · 1 site
PHASE1
other
NOT_YET_RECRUITING 120 Xuanwu Hospital, Beijing
OTHER
2025-07-08
Elderberry Functional Gum and Cognitive & Oral Health in Older Adults
NCT07054645
Elderberry Anthocyanin Chewing Gum; Placebo Chewing Gum
Runs in: Turkey (Türkiye) · 1 site
NA
other
NOT_YET_RECRUITING 34 Burdur Mehmet Akif Ersoy University
OTHER
2025-07-08
Amyloid-β Clearance Mechanisms in Alzheimer's Disease
NCT05059158
positron emission tomography (PET)
Runs in: Germany · 1 site
NA
other
RECRUITING 60 Ludwig-Maximilians - University of Munich
OTHER
2025-07-04
Biomarkers of Cognitive Impairment in Blood Cells
NCT05582941
No intervention will be performed.
Runs in: Spain · 1 site
NA
other
COMPLETED 48 University of the Balearic Islands
OTHER
2025-07-04
Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's Disease
NCT06224920
magnetic resonance imaging; electroencephalography; blood and CSF b...
NA
other
COMPLETED 140 Ludwig-Maximilians - University of Munich
OTHER
2025-07-04
Effect of Action Observation Training on Gait Variables and Global Cognitive Functions
NCT03522389
AOT with gait training; Gait training; Education
Runs in: Thailand · 1 site
NA
other
COMPLETED 39 Mahidol University
OTHER
2025-07-03
VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment
NCT03765398
VR Cognitive-motor-balance training
Runs in: United States · 1 site
NA
other
COMPLETED 27 University of Illinois at Chicago
OTHER
2025-07-03
Evaluating Rapamycin Treatment in Alzheimer's Disease Using Positron Emission Tomography
NCT06022068
Sirolimus
Runs in: Sweden · 1 site
PHASE1|PHASE2
other
COMPLETED 14 Karolinska Institutet
OTHER
2025-07-03
Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery
NCT07051096
A novel device developed providing nature-driven responsive imagery...
Runs in: Canada · 1 site
NA
other
NOT_YET_RECRUITING 60 University of British Columbia
OTHER
2025-07-03
Hypertension, Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)
NCT03354143
Standard Care; Intensive Treatment
Runs in: United States · 1 site
PHASE2
other
COMPLETED 85 University of Texas Southwestern Medical Center
OTHER
2025-07-02
Mindfulness to Reduce Loneliness in Older Caregivers
NCT04560088
Mindfulness; Breathing
Runs in: United States · 1 site
NA
other
COMPLETED 55 University of Rochester
OTHER
2025-07-02
Cognitive Rehabilitation in People With Metabolic Syndrome and Mild Cognitive Deficits
NCT05658354
Computerized cognitive program
Runs in: Greece · 1 site
NA
other
COMPLETED 50 University of Ioannina
OTHER
2025-07-02
REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)
NCT06875986
Brexpiprazole (Rexulti)
Runs in: Japan · 1 site
NA
other
RECRUITING 200 Otsuka Pharmaceutical Co., Ltd.
INDUSTRY
2025-07-02
Neuropsychological Evaluation in Intellectual Disability (ENDI)
NCT07047963
ENDI (Neuropsychological Evaluation in Intellectual Disability)
Runs in: France · 1 site
NA
other
NOT_YET_RECRUITING 40 Central Hospital, Nancy, France
OTHER
2025-07-02
Psychological Treatment to Support the Consequences of Cognitive Impairment
NCT04356924
Psychological treatment; Cognitive training
Runs in: Sweden · 1 site
NA
other
RECRUITING 138 Karolinska Institutet
OTHER
2025-07-01
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism
NCT04518059
punch skin biopsy
Runs in: United States · 2 sites
NA
other
COMPLETED 184 University Hospitals Cleveland Medical Center
OTHER
2025-07-01
Long-Term Follow-up of Gene Therapy for APOE4 Homozygote Alzheimer's Disease
NCT05400330
LX1001
Runs in: United States · 2 sites
PHASE1
gene-therapy
ACTIVE_NOT_RECRUITING 10 Lexeo Therapeutics
INDUSTRY
2025-07-01
The Effect of Occupational Activities and Finger Exercise Program on Hand Grip Strength and Activities of Daily Living in Elderly Individuals With Dementia: Randomized Controlled Trial
NCT07033338
Occupational Activities and Finger Exercise Program
Runs in: Turkey (Türkiye) · 1 site
NA
other
COMPLETED 50 Emel Dogan
OTHER
2025-07-01
Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers
NCT07041450
Digital MoCA; XpressO; MoCA; Blood-based Biomarkers (BBM); Amyloid ...
Runs in: Canada · 1 site
NA
other
RECRUITING 500 MoCA Clinic and Institute
OTHER
2025-07-01

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →