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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 5,851–5,875 of 7,816 matching trials · page 235 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Neuropsychological and Neurophysiological Effects of Cognitive Stimulation in Patients With Alzheimer's Disease and Mild Cognitive Impairment
NCT03784183
Cognitive Stimulation (CS)
Runs in: Italy · 1 site 		NA
other		 UNKNOWN 126 University of Roma La Sapienza
OTHER		 2018-12-21
The Effect of tDCS on Subcortical Brain Functioning
NCT01602276
Transcranial Direct Current Stimulation (tDCS)
Runs in: United States · 1 site 		NA
other		 TERMINATED 3 Johns Hopkins University
OTHER		 2018-12-20
Paired Integrative Home Exercise for Seniors With Dementia and Their Caregivers (PairedPLIE)
NCT02403752
Paired PLIE Program
Runs in: United States · 1 site 		NA
other		 COMPLETED 20 University of California, San Francisco
OTHER		 2018-12-19
Side Effects of Newer Antipsychotics in Older Adults
NCT00245206
Aripiprazole; Olanzapine; Risperidone
Runs in: United States · 1 site 		PHASE4
other		 COMPLETED 406 Veterans Medical Research Foundation
OTHER		 2018-12-17
The TACIT Trial: TAi ChI for People With demenTia
NCT02864056
Tai Chi
Runs in: United Kingdom · 3 sites 		NA
other		 COMPLETED 172 Bournemouth University
OTHER		 2018-12-17
Effects of Dopaminergic Therapy in Patients With Alzheimer's Disease
NCT03250741
Rotigotine transdermal patch; Placebo
Runs in: Italy · 1 site 		PHASE2
other		 COMPLETED 94 I.R.C.C.S. Fondazione Santa Lucia
OTHER		 2018-12-17
Reappraising Intergeneration Relationships in Dementia Caregiving
NCT03584568
Perspective Taking Reappraisal; Basic Skill Building
Runs in: Hong Kong · 2 sites 		NA
other		 UNKNOWN 154 The Hong Kong Polytechnic University
OTHER		 2018-12-14
Oral Health, Bite Force and Dementia
NCT03775772
Oral Health; Bite Force
Runs in: Switzerland · 1 site 		NA
other		 UNKNOWN 120 University of Zurich
OTHER		 2018-12-14
Activity of Masitinib (AB1010) in Mild to Moderate Alzheimer's Disease
NCT00976118
masitinib (AB1010); placebo 		PHASE2
anti-inflammatory		 COMPLETED 34 AB Science
INDUSTRY		 2018-12-13
Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment
NCT01299766
Behavioral Activation (BA); Supportive Therapy (ST)
Runs in: United States · 1 site 		PHASE3
other		 COMPLETED 221 Thomas Jefferson University
OTHER		 2018-12-12
Assessment of Analgesia, Sedation, Physical Restraints and Delirium in Spanish Intensive Care Units
NCT03773874
Assessment
Runs in: Spain · 1 site 		NA
other		 COMPLETED 1,574 Hospital Universitario Getafe
OTHER		 2018-12-12
A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease
NCT00838110
Dimebon; Placebo; Dimebon; Placebo
Runs in: Canada; Puerto Rico; United States · 118 sites 		PHASE3
other		 COMPLETED 742 Pfizer
INDUSTRY		 2018-12-06
Study Evaluating Intepirdine (RVT-101) in Subjects With Mild to Moderate Alzheimer's Disease on Donepezil: MINDSET Study
NCT02585934
RVT-101; Placebo
Runs in: Argentina; Australia; Bulgaria; Canada; Chile; Croatia; C... · 197 sites 		PHASE3
symptomatic-cholinergic		 COMPLETED 1,315 Axovant Sciences Ltd.
INDUSTRY		 2018-12-05
So-Lo-Mo Intervention Applied to the Smoking Cessation Process
NCT03553173
So-Lo-Mo; Psychological advice; Bupropion Pill; Varenicline Pill 		NA
other		 COMPLETED 240 Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
OTHER		 2018-12-04
A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease
NCT00566397
PF-04494700; PF-04494700; Placebo
Runs in: United States · 62 sites 		PHASE2
other		 COMPLETED 402 Pfizer
INDUSTRY		 2018-11-30
The Effect of Solving Jigsaw Puzzles on Visuospatial Cognition in Older Adults: Jigsaw Puzzles As Cognitive Enrichment
NCT02667314
Jigsaw puzzles; Cognitive health counseling
Runs in: Germany · 1 site 		NA
other		 COMPLETED 100 University of Ulm
OTHER		 2018-11-30
Retinal Nerve Fiber Layer Thickness and Cerebrospinal Fluid Aβ/Tau
NCT03447613
surgery
Runs in: China · 1 site 		NA
other		 COMPLETED 86 Shanghai 10th People's Hospital
OTHER		 2018-11-30
Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo
NCT02240693
BI 409306; Placebo; BI 409306; Placebo; Placebo; BI 409306; BI 4093...
Runs in: Austria; Belgium; Canada; France; Germany; Italy; Netherl... · 52 sites 		PHASE2
other		 COMPLETED 128 Boehringer Ingelheim
INDUSTRY		 2018-11-28
Phase 2a Dose Finding, PK/PD and 12 Month Exploratory Efficacy Study of ANAVEX2-73 in Patients With Alzheimer's Disease
NCT02244541
ANAVEX2-73 Oral; ANAVEX2-73 Intravenous; ANAVEX2-73 Oral; ANAVEX2-73 Oral
Runs in: Australia · 5 sites 		PHASE2
other		 COMPLETED 32 Anavex Life Sciences Corp.
INDUSTRY		 2018-11-28
Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children
NCT00857727
Dexmedetomidine; Saline
Runs in: United States · 1 site 		PHASE3
other		 COMPLETED 33 St. Luke's-Roosevelt Hospital Center
OTHER		 2018-11-27
Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction
NCT02045004
Runs in: Switzerland · 1 site 		NA
other		 COMPLETED 100 Nicolai Goettel
OTHER		 2018-11-23
Imaging Tau in Alzheimer's Disease and Normal Aging
NCT02884492
18F-THK-5351; Lumbar Puncture (optional)
Runs in: United States · 1 site 		PHASE2
other		 TERMINATED 17 William Charles Kreisl
OTHER		 2018-11-19
Recollection Training in Healthy Older Adults and Older Adults With Amnestic Mild Cognitive Impairment
NCT00643266
Recollection Training; Control
Runs in: Canada · 1 site 		NA
other		 COMPLETED 91 Baycrest
OTHER		 2018-11-16
Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia
NCT00782067
Midostaurin (PKC412)
Runs in: Australia; Austria; Belgium; Canada; France; Germany; Net... · 29 sites 		PHASE2
other		 COMPLETED 116 Novartis Pharmaceuticals
INDUSTRY		 2018-11-15
BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.
NCT02337907
Placebo; Placebo; BI 409306; Donepezil
Runs in: Austria; Belgium; Canada; France; Germany; Italy; Netherl... · 60 sites 		PHASE2
symptomatic-cholinergic		 COMPLETED 329 Boehringer Ingelheim
INDUSTRY		 2018-11-14

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →