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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 4,726–4,750 of 7,816 matching trials · page 190 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease
NCT01584440
AVP-923-20; Placebo; AVP-923-30
Runs in: United States · 44 sites 		PHASE2
other		 COMPLETED 220 Avanir Pharmaceuticals
INDUSTRY		 2021-11-26
Group Therapy For Dementia Caregivers At Risk For Complicated Grief
NCT03177772
Pre-loss group therapy
Runs in: United States · 3 sites 		NA
other		 COMPLETED 80 University of Utah
OTHER		 2021-11-23
ENgaging in Advance Care Planning Talks Group Visit Intervention for Cognitive Impairment
NCT03711396
Advance Care Planning Group Visits
Runs in: United States · 2 sites 		NA
other		 COMPLETED 26 University of Colorado, Denver
OTHER		 2021-11-22
The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI)
NCT05009524
iPACES (interactive Physical and Cognitive Exercise System); PACE (...
Runs in: United States · 1 site 		NA
other		 UNKNOWN 120 iPACES LLC
INDUSTRY		 2021-11-22
A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's Disease
NCT03019289
pridopidine (90 mg)
Runs in: Germany · 1 site 		PHASE1
other		 COMPLETED 23 Prilenia
INDUSTRY		 2021-11-19
The Effect of Music in Alzheimer's Patients
NCT05125536
Music therapy
Runs in: Turkey (Türkiye) · 1 site 		NA
other		 COMPLETED 30 Eskisehir Osmangazi University
OTHER		 2021-11-18
Open-Label Extension Study of 23 mg Donepezil SR in Participants With Moderate to Severe Alzheimer's Disease
NCT00566501
Donepezil
Runs in: United States · 1 site 		PHASE3
symptomatic-cholinergic		 COMPLETED 915 Eisai Inc.
INDUSTRY		 2021-11-17
Computer Games to Prevent Mild Cognitive Impairment and Dementia
NCT02310620
Cognitive training
Runs in: Hungary · 1 site 		NA
other		 COMPLETED 109 Semmelweis University
OTHER		 2021-11-17
Speed of Processing Training for Cognitive Deficits After Delirium in Older Adults
NCT03342989
Speed of Processing Training; Internet-Based Contact Control
Runs in: United States · 1 site 		NA
other		 TERMINATED 17 University of Alabama at Birmingham
OTHER		 2021-11-16
I2PETHV - Imidazoline2 Binding Site in Healthy Volunteers
NCT02323217
[11C]BU99008; Idazoxan; Isocarboxazid
Runs in: United Kingdom · 1 site 		EARLY_PHASE1
other		 COMPLETED 20 Imperial College London
OTHER		 2021-11-15
Characteristics of Patients With Dementia Who Are Screaming in Nursing Homes
NCT04760015
Runs in: France · 1 site 		NA
other		 COMPLETED 60 University Hospital, Montpellier
OTHER		 2021-11-15
Volumetric Magnetic Resonance Imaging in Dementia
NCT05119114
Magnetic Resonance Imaging (MRI)
Runs in: Egypt · 1 site 		NA
other		 UNKNOWN 40 Assiut University
OTHER		 2021-11-12
The Relevance of the Blood-brain Barrier to Cognitive Dysfunction and Alzheimer's Disease
NCT04093882
Contrast agent enhanced MRI using Gadovist
Runs in: Germany · 1 site 		NA
other		 COMPLETED 101 Charite University, Berlin, Germany
OTHER		 2021-11-11
Effectiveness of Walking Exercise in Improving Cognitive Function in Older Adults With Mild Cognitive Impairment
NCT04515563
Stretching exercise; Low-frequency, moderate-intensity walking grou...
Runs in: Hong Kong · 1 site 		NA
other		 COMPLETED 50 The University of Hong Kong
OTHER		 2021-11-11
Art Museum Program for Seniors With Cognitive Disorders and Care-partners
NCT04696549
Virtual visual art experience guided by Visual Thinking Strategies
Runs in: United States · 1 site 		NA
other		 COMPLETED 6 Johns Hopkins University
OTHER		 2021-11-11
Neural Correlates In Mild Alzheimer's Disease
NCT00477659
Donepezil hydrochloride
Runs in: United States · 1 site 		PHASE4
symptomatic-cholinergic		 COMPLETED 14 Eisai Inc.
INDUSTRY		 2021-11-10
Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease
NCT02547818
ALZT-OP1a; ALZT-OP1b; Placebo ALZT-OP1a; Placebo ALZT-OP1b
Runs in: Australia; Bulgaria; Canada; Czechia; Hungary; Poland; Un... · 121 sites 		PHASE3
other		 COMPLETED 620 AZTherapies, Inc.
INDUSTRY		 2021-11-10
Efficacy and Safety of Donepezil and Sodium Oligomannate in Patients With Mild to Moderate Alzheimer's Disease
NCT05114499
Donepezil; GV-971 		NA
symptomatic-cholinergic		 UNKNOWN 150 First Affiliated Hospital Xi'an Jiaotong University
OTHER		 2021-11-10
An Intervention Study to Reduce Drug-related Problems and Readmissions Among Old People With Dementia
NCT01504672
Medication review
Runs in: Sweden · 2 sites 		NA
other		 COMPLETED 460 Umeå University
OTHER		 2021-11-09
Alternatives for Reducing Chorea in Huntington Disease
NCT01897896
SD-809
Runs in: Australia; Canada; United States · 38 sites 		PHASE3
other		 COMPLETED 119 Auspex Pharmaceuticals, Inc.
INDUSTRY		 2021-11-09
Association of Cognition With Functional Mobility in People With Alzheimer's Disease
NCT05113732
Runs in: Turkey (Türkiye) · 1 site 		NA
other		 UNKNOWN 64 Istanbul University - Cerrahpasa
OTHER		 2021-11-09
Task-Based Grounding Program
NCT04648553
Task-Based Grounding; Connected Care (Enhanced Treatment as usual)
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 28 Dartmouth-Hitchcock Medical Center
OTHER		 2021-11-08
Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1
NCT00000738
Nimodipine; Zidovudine
Runs in: United States · 12 sites 		PHASE1
other		 COMPLETED 36 National Institute of Allergy and Infectious Diseases (NIAID)
NIH		 2021-11-04
Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex
NCT00000657
Zidovudine; Didanosine
Runs in: United States · 13 sites 		PHASE2
other		 COMPLETED 80 National Institute of Allergy and Infectious Diseases (NIAID)
NIH		 2021-11-03
A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection
NCT00000702
Zidovudine
Runs in: United States · 21 sites 		PHASE3
other		 COMPLETED 315 National Institute of Allergy and Infectious Diseases (NIAID)
NIH		 2021-11-03

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →