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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 3,851–3,875 of 7,816 matching trials · page 155 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation
NCT05321498
XPro1595; Placebo 		PHASE2
other		 WITHDRAWN 0 Inmune Bio, Inc.
INDUSTRY		 2023-09-28
Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease
NCT05709301
Donepezil Hydrochloride; Placebo 		PHASE2
symptomatic-cholinergic		 UNKNOWN 120 Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
OTHER		 2023-09-28
Development of the Virtual Unified Huntington's Disease Rating Scale
NCT05748288
Runs in: United States · 17 sites 		NA
other		 COMPLETED 60 Huntington Study Group
NETWORK		 2023-09-28
E-health Enhanced Motor-cognitive Training for AED Discharged Older Adults With Cognitive Frailty
NCT05750121
E-health enhanced motor-cognitive training
Runs in: Hong Kong · 1 site 		NA
other		 UNKNOWN 40 The Hong Kong Polytechnic University
OTHER		 2023-09-28
Medicare Anti-Aβ mAb Coverage With Evidence Development (CED) Study
NCT06058234
Monoclonal Antibodies Directed Against Amyloid for the Treatment of...
Runs in: United States · 1 site 		NA
other		 RECRUITING 8,680 Centers for Medicare and Medicaid Services/ Coverage and Analysis Group
OTHER_GOV		 2023-09-28
Effects of Transcutaneous Electrical Nerve Stimulation (TENS) to Improve the Cognitive Functions in Older Adults
NCT05408689
T1 TENS; Concha TENS; Control
Runs in: Hong Kong · 1 site 		NA
other		 COMPLETED 90 The Hong Kong Polytechnic University
OTHER		 2023-09-22
Longitudinal Quantitative Susceptibility Mapping (QSM) in Alzheimer 's Disease
NCT02752750
MRI 		NA
other		 UNKNOWN 50 Medical University of Graz
OTHER		 2023-09-21
Systematic Multi-domain Alzheimer's Risk Reduction Trial
NCT03683394
SMARRT Intervention; Health Education Intervention
Runs in: United States · 1 site 		NA
other		 COMPLETED 172 Kaiser Permanente
OTHER		 2023-09-21
An Observational Study Using Multimodal Sensors to Measure Cognitive Health in Adults and Distinguish Mild Cognitive Impairment From Normal Aging
NCT05058950
Runs in: United States · 1 site 		NA
other		 TERMINATED 22,720 Biogen
INDUSTRY		 2023-09-21
Mindfulness-Based VR for Family Caregivers of People With Dementia
NCT06034249
Mindfulness-Based VR; Audio
Runs in: Taiwan · 1 site 		NA
other		 COMPLETED 16 Taipei Medical University
OTHER		 2023-09-21
Cognitive Impairment and Fatigue After Mild to Moderate COVID-19
NCT06042530
Neuropsychological investigation; Optometric investigation; Magneti...
Runs in: Sweden · 1 site 		NA
other		 UNKNOWN 100 Danderyd Hospital
OTHER		 2023-09-21
A Feasibility Study of Online Psychoeducation for Family Caregivers of People With Dementia
NCT06042634
Online psychoeducation; Face-to-face psychoeducation
Runs in: Hong Kong · 1 site 		NA
other		 COMPLETED 60 Chinese University of Hong Kong
OTHER		 2023-09-21
Feasibility Study of Game Technology in the Early Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
NCT06047340
G:DATA, dementia screen videogame
Runs in: United Kingdom · 1 site 		NA
other		 UNKNOWN 30 Ascentys Ltd
INDUSTRY		 2023-09-21
Benefit of Virtual Reality Headset Use on Apathy in Older Adults With Major Neurocognitive Disorders
NCT06047522
Casque Lumeen
Runs in: France · 6 sites 		NA
other		 UNKNOWN 30 RIVAGES
OTHER		 2023-09-21
Virtual Reality Training for Aggression Control
NCT06047587
VR-TrAC; Care as Usual
Runs in: Netherlands · 1 site 		NA
other		 UNKNOWN 128 University Medical Center Groningen
OTHER		 2023-09-21
18F-florbetaben PET-CT to Non-invasively Diagnose Cardiac AL Amyloidosis
NCT06048601
18F-florbetaben PET/CT
Runs in: Italy · 1 site 		NA
other		 UNKNOWN 150 Fondazione Toscana Gabriele Monasterio
OTHER		 2023-09-21
Treatment of Severe Destructive Behavior: FCT Versus Wait-List Control
NCT02483572
Functional Communication Training
Runs in: United States · 1 site 		NA
other		 TERMINATED 4 University of Nebraska
OTHER		 2023-09-18
Computer Training and Transcranial Direct Current Stimulation for Cognition in HIV
NCT03440840
Transcranial Direct Current Stimulation (tDCS); Computer-based Cogn...
Runs in: United States · 1 site 		NA
other		 COMPLETED 46 Nova Southeastern University
OTHER		 2023-09-18
A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type
NCT03548584
Brexpiprazole; Placebo
Runs in: United States · 1 site 		PHASE3
other		 COMPLETED 345 Otsuka Pharmaceutical Development & Commercialization, Inc.
INDUSTRY		 2023-09-18
Wii-fit for Activity, Balance and Gait in Assisted Living
NCT01000038
Wii-Fit intervention; Walking
Runs in: United States · 1 site 		NA
other		 COMPLETED 22 University of Nebraska
OTHER		 2023-09-15
Clinical Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients
NCT05043675
[18F]APN-1607
Runs in: China · 1 site 		EARLY_PHASE1
other		 UNKNOWN 6 Nanjing First Hospital, Nanjing Medical University
OTHER		 2023-09-14
Immunohistochemical Study of Neurodegenerative Diseases
NCT05518409
Detection of cytof in peripheral PBMC; Donepezil for patients with ...
Runs in: China · 1 site 		NA
symptomatic-cholinergic		 UNKNOWN 100 First Affiliated Hospital of Zhejiang University
OTHER		 2023-09-14
Premature Enhanced Automated Capture of Comfort Knowledge
NCT06037629
Runs in: United Kingdom · 1 site 		NA
other		 UNKNOWN 100 Newcastle University
OTHER		 2023-09-14
Cognitive Stimulation in Elderly Individuals at Risk to Develop Dementia (Allena-Mente).
NCT01793493
Cognitive stimulation; Sanitary education
Runs in: Italy · 1 site 		NA
other		 COMPLETED 121 Fondazione Golgi Cenci
OTHER		 2023-09-13
Addressing Dementia Via Agitation-Centered Evaluation
NCT03226522
AXS-05; Bupropion; Placebo
Runs in: Australia; United States · 78 sites 		PHASE2|PHASE3
other		 COMPLETED 366 Axsome Therapeutics, Inc.
INDUSTRY		 2023-09-13

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →