alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 2,551–2,575 of 7,816 matching trials · page 103 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Assessing the Effectiveness of an Approach for Vocal Behaviors in Older People Living in Nursing Homes
NCT03506672
Approach based on the meanings of vocal behaviours; Usual practices
Runs in: Canada · 7 sites 		NA
other		 COMPLETED 157 Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
OTHER		 2025-04-25
Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)
NCT03740178
MK-4334; Placebo to MK-4334; Donepepzil 		PHASE1
other		 WITHDRAWN 0 Merck Sharp & Dohme LLC
INDUSTRY		 2025-04-25
Functionally-tailored Oral Care Intervention for Community-dwelling Older Adults With Dementia and Their Caregivers
NCT04238520
Functionally Tailored Oral Care Intervention; Control Intervention
Runs in: United States · 1 site 		NA
other		 COMPLETED 26 Xi Chen
OTHER		 2025-04-25
Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation
NCT06945614
Xenon gas inhalation
Runs in: United States · 1 site 		PHASE1
other		 RECRUITING 16 General Biophysics LLC
INDUSTRY		 2025-04-25
Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia
NCT04486586
Active tDCS plus Speech-Language Therapy; Sham plus Speech-Language Therapy
Runs in: United States · 1 site 		NA
other		 WITHDRAWN 0 Johns Hopkins University
OTHER		 2025-04-24
Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping
NCT06941662
computer vision, remote monitoring, blood, urine, wrist bands, mobile-app
Runs in: United States · 1 site 		NA
other		 RECRUITING 200 Stanford University
OTHER		 2025-04-24
Personalized Medicine in the Elderly With Vision Impairment and Mild Cognitive Impairment
NCT06942728
nLIFE EyeFitness
Runs in: Italy · 1 site 		NA
other		 NOT_YET_RECRUITING 24 Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER		 2025-04-24
A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease
NCT05310071
Aducanumab; Placebo
Runs in: Australia; Belgium; Brazil; Canada; Finland; France; Germ... · 265 sites 		PHASE3
anti-amyloid-antibody		 TERMINATED 1,027 Biogen
INDUSTRY		 2025-04-23
ASURE: Alzheimer Study Using oRal Edaravone
NCT05323812
TW001; Placebo
Runs in: Croatia; Netherlands · 6 sites 		PHASE2
other		 COMPLETED 61 Treeway B.V.
INDUSTRY		 2025-04-23
ScentAware and OCT in MCI vs HC
NCT06377241
ScentAware; UPSIT
Runs in: United States · 1 site 		NA
other		 TERMINATED 20 University of Wisconsin, Madison
OTHER		 2025-04-23
Responding to Elder Abuse in GERiAtric Care - Dementia
NCT06659822
Runs in: Sweden · 2 sites 		NA
other		 COMPLETED 216 Region Östergötland
OTHER		 2025-04-23
The REMINDER Program for Older Adults Supported by Residential and Daycare Facilities
NCT06733181
REMINDER intervention
Runs in: Portugal · 1 site 		NA
other		 COMPLETED 25 University of Coimbra
OTHER		 2025-04-23
Simufilam (PTI-125), 100 mg, for Mild-to-moderate Alzheimer's Disease Patients
NCT04388254
Simufilam 100 mg oral tablet; Placebo
Runs in: Canada; United States · 17 sites 		PHASE2
other		 COMPLETED 220 Cassava Sciences, Inc.
INDUSTRY		 2025-04-22
Moving Together: An Online Group Movement Program for People Living With Memory Loss and Caregivers
NCT04621448
Moving Together
Runs in: United States · 1 site 		NA
other		 COMPLETED 224 University of California, San Francisco
OTHER		 2025-04-22
Cognitive Stimulation and Strength Training in Older Adults With Cognitive Impairment
NCT06666088
Cognitive stimulation and Strength training
Runs in: Spain · 1 site 		NA
other		 COMPLETED 81 University of Jaén
OTHER		 2025-04-22
Investigation of Different Rehabilitation Approaches in Older Adults With Mild Cognitive Impairment
NCT06837493
Resistance based hand exercises and functional task-oriented hand e...
Runs in: Turkey (Türkiye) · 1 site 		NA
other		 COMPLETED 47 Uşak University
OTHER		 2025-04-22
Does EVOO Induce Gene and Metabolic Changes in Healthy Subjects
NCT05929924
Extra virgin olive oil
Runs in: United States · 1 site 		NA
other		 ACTIVE_NOT_RECRUITING 40 Augusta University
OTHER		 2025-04-20
Early-phase Telecare Programs for Minor Stroke
NCT06306144
Psychoeducation; Computerised Cognitive Stimulation; Usual Care
Runs in: France · 3 sites 		NA
other		 NOT_YET_RECRUITING 80 Hospices Civils de Lyon
OTHER		 2025-04-18
Kimel Family Centre for Brain Health and Wellness
NCT06933667
Physical Activity; Brain-healthy Eating; Cognitive Engagement; Soci...
Runs in: Canada · 1 site 		NA
other		 RECRUITING 450 Baycrest
OTHER		 2025-04-18
Imaging Inflammation in Alzheimer's Disease With 11C-ER176
NCT03744312
11C-ER176; Florbetaben
Runs in: United States · 1 site 		PHASE1|PHASE2
other		 COMPLETED 9 Columbia University
OTHER		 2025-04-17
A Novel Therapeutic Target for Alzheimer's Disease in Men and Women 50-85 Years of Age.
NCT03752294
Dabigatran; Placebo - Cap 		PHASE1
other		 WITHDRAWN 0 University of Rhode Island
OTHER		 2025-04-17
Hearing Aid and Individuals With Cognitive Disorders
NCT04049643
Audiologist-based fitting; Service-only Fitting; Device-only fitting
Runs in: United States · 2 sites 		NA
other		 COMPLETED 17 Yu-Hsiang Wu
OTHER		 2025-04-17
First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
NCT05374278
[18F]RP-115 PET/MRI or PET/CT and MRI
Runs in: United States · 1 site 		PHASE1|PHASE2
other		 RECRUITING 102 David Wilson
OTHER		 2025-04-17
At Home Gamma tACS in Alzheimer's Disease (tACS@Home)
NCT05643326
40 Hz transcranial alternating current stimulation; Sham stimulation
Runs in: Italy · 1 site 		NA
other		 COMPLETED 53 Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
OTHER		 2025-04-17
Reminiscence Therapy in Individuals With Dementia
NCT06180694
Reminiscence therapy
Runs in: Turkey (Türkiye) · 1 site 		NA
other		 COMPLETED 28 Amasya University
OTHER		 2025-04-17

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →