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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 1–25 of 566 matching trials (filtered from 7,816) · page 1 of 23, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
NCT05048966
Group Wellness Class 1; Group Wellness Class 2
Runs in: United States · 1 site 		NA
other		 RECRUITING 360 Kessler Foundation
OTHER		 2026-09-21
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
NCT05456503
[18F]-PI-2620
Runs in: United States · 1 site 		PHASE3
other		 RECRUITING 72 University of Pennsylvania
OTHER		 2026-09-21
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
NCT06041789
Donepezil; Memantine
Runs in: United States · 1 site 		PHASE2
symptomatic-cholinergic		 RECRUITING 45 Duke University
OTHER		 2026-09-21
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
NCT06847321
LHP588; LHP588; Placebo Drug
Runs in: United States · 39 sites 		PHASE2
other		 RECRUITING 300 Lighthouse Pharmaceuticals, Inc.
INDUSTRY		 2026-09-21
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
NCT07099053
Runs in: United States · 1 site 		NA
other		 RECRUITING 400 National Institute on Aging (NIA)
NIH		 2026-09-21
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
NCT07169630
18F-PF974; 18F-florbetaben
Runs in: United States · 1 site 		PHASE1
other		 RECRUITING 90 National Institute of Mental Health (NIMH)
NIH		 2026-09-21
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
NCT07177352
No Intervention
Runs in: Argentina; Australia; Brazil; Canada; Chile; China; Denma... · 229 sites 		PHASE3
other		 RECRUITING 80,000 Hoffmann-La Roche
INDUSTRY		 2026-09-21
Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease
NCT07378644
SKY-0515; SKY-0515 Placebo
Runs in: Argentina; Brazil; Canada; Chile; Colombia; Georgia; Germ... · 24 sites 		PHASE2|PHASE3
other		 RECRUITING 400 Skyhawk Therapeutics, Inc.
INDUSTRY		 2026-09-21
The Gut - PRO Study
NCT07413744
Probiotic; Placebo
Runs in: United States · 1 site 		PHASE1
other		 RECRUITING 40 University of Wisconsin, Madison
OTHER		 2026-09-21
Escalating Doses of Memantine in Down Syndrome (MEDS-123)
NCT07531940
Memantine
Runs in: United States · 1 site 		PHASE1
symptomatic-cholinergic		 NOT_YET_RECRUITING 25 University Hospitals Cleveland Medical Center
OTHER		 2026-09-21
Music for Pain and Dementia
NCT07602283
Drumming session; Music-listening session
Runs in: United States · 1 site 		NA
other		 RECRUITING 60 Yale University
OTHER		 2026-09-21
Comparing Two Acute Care Transition Programs for Older Adults and Their Family Caregivers
NCT07661355
Patient-Centered Program; Family Caregiver Enhanced Program
Runs in: United States · 4 sites 		NA
other		 RECRUITING 2,560 Wake Forest University Health Sciences
OTHER		 2026-09-21
Microbiome in Aging of Gut and Brain
NCT07799402
Runs in: United States · 1 site 		NA
other		 RECRUITING 700 University of South Florida
OTHER		 2026-09-21
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
NCT04396873
11C-MC1; 11C-PS13; 18f-florbetaben
Runs in: United States · 1 site 		PHASE1
other		 RECRUITING 184 National Institute of Mental Health (NIMH)
NIH		 2026-09-18
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
NCT07599670
ABBV-1758; Placebo for ABBV-1758; ABBV-1758; Placebo for ABBV-1758
Runs in: China; United States · 13 sites 		PHASE1|PHASE2
other		 RECRUITING 210 AbbVie
INDUSTRY		 2026-09-18
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
NCT03225144
Runs in: United States · 1 site 		NA
other		 RECRUITING 360 National Institute of Neurological Disorders and Stroke (NINDS)
NIH		 2026-09-17
Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease
NCT05295615
ECHS AD Device
Runs in: United States · 1 site 		NA
other		 RECRUITING 40 Herrick Medical LLC
INDUSTRY		 2026-09-17
Pulsed Electromagnetic Field Treatment With Dementia Patients
NCT06862557
ECHS AD Device
Runs in: United States · 1 site 		NA
other		 RECRUITING 48 Herrick Medical LLC
INDUSTRY		 2026-09-17
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
NCT06976203
KarXT; KarX-EC; Placebo
Runs in: Argentina; Australia; Brazil; Finland; France; Germany; G... · 127 sites 		PHASE3
other		 RECRUITING 586 Bristol-Myers Squibb
INDUSTRY		 2026-09-17
Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)
NCT07216950
Knowledge and Interpersonal Skills to Develop Enhanced Relationship...
Runs in: United States · 1 site 		NA
other		 NOT_YET_RECRUITING 260 Case Western Reserve University
OTHER		 2026-09-17
Pridopidine Phase 3 Study in Huntington's Disease
NCT07609108
Pridopidine; Placebo
Runs in: Belgium; Canada; Czechia; France; Germany; Italy; Netherl... · 66 sites 		PHASE3
other		 RECRUITING 400 Prilenia
INDUSTRY		 2026-09-17
Percepta for Cognitive Optimization
NCT07612449
Percepta; Placebo
Runs in: United States · 1 site 		NA
other		 RECRUITING 154 Cerebrum DAO Association
OTHER		 2026-09-17
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
NCT07721467
Psilocybin; Cognitive Training
Runs in: United States · 1 site 		PHASE2
other		 NOT_YET_RECRUITING 200 National Institute on Aging (NIA)
NIH		 2026-09-17
Adaptango Performance PRocess for Older Adults Community reHabilitation
NCT07824128
Adaptango Performance Process (APP) program
Runs in: United States · 1 site 		NA
other		 NOT_YET_RECRUITING 120 Emory University
OTHER		 2026-09-17
Advancing Ethical Goals In Society Trial
NCT07824245
ACP Counselor Video Program
Runs in: United States · 2 sites 		NA
other		 NOT_YET_RECRUITING 12,174 Tufts Medical Center
OTHER		 2026-09-17

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarized in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →