trajectories

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

1. 71/100

   Blood biomarkers of Alzheimer's disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study

   ✓ Peer-reviewed alzhub usefulness score 71 out of 100. The lancet. Healthy longevity · 2025-05-22 · Biomarkers

   In adjusted models, higher concentrations of p-tau181 (β per year 0·93 [95% CI 0·71 to 1·16]; p<0·0001), p-tau217 (β per year 1·31 [1·03 to 1·58]; p<0·0001), neurofilament light chain (β per year 0·76 [0·56 to 0·96]; p<0·0001), and GFAP (β per year 0·37 [0·21 to 0·53]; p<0·0001) were associated with an accelerated decline of chair-stand performance over time.

   • Biomarkers
2. 72/100

   Interactions between vascular burden and amyloid-β pathology on trajectories of tau accumulation

   ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Brain : a journal of neurology · 2024-03-01 · Brain scans and imaging

   To validate our in vivo results, we examined 1610 autopsy cases from an Arizona-based neuropathology cohort on three main vascular pathological features: cerebral amyloid angiopathy; white matter rarefaction; and infarcts.

   • Brain Biology
3. 62/100

   Temporal trajectories of in vivo tau and amyloid-β accumulation in Alzheimer's disease

   ✓ Peer-reviewed alzhub usefulness score 62 out of 100. European journal of nuclear medicine and molecular imaging · 2020-04-29 · Brain scans and imaging

   Sequential appearance of Aβ and tau accumulation supports a hypothetical dynamic biomarker model and Braak's hierarchical tau spreading model in AD.

   • Brain Scans

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