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Home › Research › Topics › thk5351

thk5351

3 studies tagged thk5351, dated 2017-08-12 to 2018-10-05. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer's Disease: A PET (THK5351, PiB) and Resting fMRI Study 2018-10-05
  2. Head to head comparison of [18F] AV-1451 and [18F] THK5351 for tau imaging in Alzheimer's disease and frontotemporal dementia 2017-11-16
  3. Tau positron emission tomography using [18F]THK5351 and cerebral glucose hypometabolism in Alzheimer's disease 2017-08-12

Studies

3 studies carry this tag.

Date range

2017 to 2018

Top journals

  • European journal of nuclear medicine and molecular imaging 1
  • Frontiers in aging neuroscience 1
  • Neurobiology of aging 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer's Disease: A PET (THK5351, PiB) and Resting fMRI Study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Frontiers in aging neuroscience 2018-10-05 Brain scans and imaging

    SSM/PCA identified a significant spatial THK5351 pattern composed by mainly three clusters including precuneus/posterior cingulate cortex (PCC), right and left dorsolateral prefrontal cortex (DLPFC) which accounted for 23.6% of the total subject voxel variance of the data and had 82.6% sensitivity and 79.1% specificity in discriminating AD from healthy controls.

  2. Head to head comparison of [18F] AV-1451 and [18F] THK5351 for tau imaging in Alzheimer's disease and frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. European journal of nuclear medicine and molecular imaging 2017-11-16 Brain scans and imaging

    AV-1451 is more sensitive and specific to Alzheimer's disease type tau and shows lower off-target binding, while THK5351 may mirror non-specific neurodegeneration.

  3. Tau positron emission tomography using [18F]THK5351 and cerebral glucose hypometabolism in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurobiology of aging 2017-08-12 Brain scans and imaging

    This study aims to evaluate the clinical validity of [ 18 F]THK5351 positron emission tomography (PET) for the assessment of disease progression and symptoms in Alzheimer's disease (AD).

All topic tags with their study counts