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tauopathy-mice
2 studies tagged tauopathy-mice, dated 2023-10-19 to 2025-01-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- The GLP-1 agonist semaglutide ameliorates cognitive regression in P301S tauopathy mice model via autophagy/ACE2/SIRT1/FOXO1-Mediated Microglia Polarization 2025-01-26
- Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice 2023-10-19
Studies
2 studies carry this tag.
Date range
2023 to 2025
Top journals
- Acta neuropathologica communications 1
- European journal of pharmacology 1
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Tau hyper-phosphorylation has been recognized as an essential contributor to neurodegeneration in Alzheimer's disease (AD) and related tauopathies.
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Tau tubulin kinase-1 (TTBK1), a neuron-specific tau kinase, is highly expressed in the entorhinal cortex and hippocampal regions, where early tau pathology evolves in Alzheimer's disease (AD).