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tau-epitope
5 studies tagged tau-epitope, dated 1993-01-01 to 2019-10-17. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology 2019-10-17
- Neurofibrillary tangles in progressive supranuclear palsy contain the same tau epitopes identified in Alzheimer's disease PHFtau 1996-05-01
- Constitutive Alzheimer's-type tau epitopes in a neuritogenic rat CNS cell line 1995-07-01
Studies
5 studies carry this tag.
Date range
1993 to 2019
Top journals
- Acta neuropathologica 1
- Experimental neurology 1
- Journal of neuropathology and experimental neurology 1
- Neurobiology of aging 1
- Neurobiology of disease 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Abnormal tau hyperphosphorylation and its aggregation into neurofibrillary tangles are a hallmark of tauopathies, neurodegenerative disorders that include Alzheimer's disease (AD).
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Neurofibrillary tangle (NFT)-rich brain samples from patients with progressive supranuclear palsy (PSP) or Alzheimer's disease (AD) were probed with a large panel of anti-tau antibodies to compare the species of tau present in PSP and AD NFTs by immunohistochemistry and Western blot methods.
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Paired helical filaments (PHFs) of Alzheimer's disease (AD) largely comprise hyperphosphorylated forms of the cytoskeletal protein tau.
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The monoclonal antibody PHF-1 recognizes phosphorylated tau isoforms present in paired helical filaments of Alzheimer's disease.
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An immunocytochemical study of Alzheimer's disease hippocampus with a panel of anti-tau antibodies revealed two antibodies that stained granulovacuolar bodies (GVB) in pyramidal neurons of Ammon's horn.