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Home › Research › Topics › target

target

5 studies tagged target, dated 2008-05-16 to 2023-08-04. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Underlying Mechanisms of Brain Aging and Neurodegenerative Diseases as Potential Targets for Preventive or Therapeutic Strategies Using Phytochemicals 2023-08-04
  2. Microglia: A pharmacological target for the treatment of age-related cognitive decline and Alzheimer's disease 2023-02-09
  3. DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease 2013-09-11

Studies

5 studies carry this tag.

Date range

2008 to 2023

Top journals

  • Brain : a journal of neurology 1
  • Chemical research in toxicology 1
  • Frontiers in pharmacology 1
  • Molecular & cellular proteomics : MCP 1
  • Nutrients 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Underlying Mechanisms of Brain Aging and Neurodegenerative Diseases as Potential Targets for Preventive or Therapeutic Strategies Using Phytochemicals

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Nutrients 2023-08-04 TREM2 and immune genetics

    During aging, several tissues and biological systems undergo a progressive decline in function, leading to age-associated diseases such as neurodegenerative, inflammatory, metabolic, and cardiovascular diseases and cancer.

  2. Microglia: A pharmacological target for the treatment of age-related cognitive decline and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in pharmacology 2023-02-09 TREM2 and immune genetics

    As individuals age, microglia, the resident immune cells of the central nervous system (CNS), become less effective at preserving brain circuits.

  3. DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Brain : a journal of neurology 2013-09-11 Genetics

    The central nervous system has a pattern of gene expression that is closely regulated with respect to functional and anatomical regions.

  4. Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: nucleophilic targets and adduct formation

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Chemical research in toxicology 2009-09-01 Genetics

    Acrolein and 4-hydroxy-2-nonenal (HNE) are byproducts of lipid peroxidation and are thought to play central roles in various traumatic injuries and disease states that involve cellular oxidative stress, for example, spinal cord trauma, diabetes, and Alzheimer's disease.

  5. Targets of caspase-6 activity in human neurons and Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Molecular & cellular proteomics : MCP 2008-05-16 Genetics

    Caspase-6 activation occurs early in Alzheimer disease and sometimes precedes the clinical manifestation of the disease in aged individuals.

All topic tags with their study counts